Difference between revisions of "Amyloid-producing Odontogenic Tumour"
Jump to navigation
Jump to search
(32 intermediate revisions by 4 users not shown) | |||
Line 1: | Line 1: | ||
− | {{ | + | {{unfinished}} |
− | |||
− | |||
− | |||
− | |||
+ | {{dog}} | ||
+ | {{cat}} | ||
==Typical Signalment== | ==Typical Signalment== | ||
− | This is a | + | *This is a common odontogenic tumour in cats. |
+ | *More rarely found in dogs. | ||
+ | ==Description== | ||
+ | The lesions appear as masses that are friable and ulcerated. Many amyloid-producing odontogenic tumours are [[Neoplasia - Pathology#Nomenclature|melanotic]] which makes them difficult to distinguish from the more aggressive malignant melanoma. They can erode but not infiltrate adjacent bone. | ||
+ | |||
==Diagnosis== | ==Diagnosis== | ||
+ | |||
===Clinical Signs=== | ===Clinical Signs=== | ||
− | + | *halitosis | |
+ | *oral bleeding | ||
+ | *dental disruption or loss | ||
+ | *facial or mandibular deformity | ||
+ | *excessive salivation | ||
+ | *growth protruding from the mouth | ||
+ | *dysphagia occurs rarely | ||
===Diagnostic Imaging=== | ===Diagnostic Imaging=== | ||
− | Skull radiography may show a soft tissue opacity with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a | + | Skull radiography may show a soft tissue opacity with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a dignostic possibility, thoracic radiography should be carried out to evaluate for lung metastases. |
+ | ===Biopsy=== | ||
− | + | Required for a definitive diagnosis | |
− | + | *Incisional Biopsy - best | |
− | Incisional | + | *Cytological or grab procedures - difficult to obtain a representative sample |
Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated. | Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated. | ||
==Treatment== | ==Treatment== | ||
− | Surgical excision with narrow margins is normally sufficient. | + | *Surgical excision with narrow margins is normally sufficient. |
− | Radiation therapy should be considered in cases of incomplete surgical excision. | + | *Radiation therapy should be considered in cases of incomplete surgical excision. |
==Prognosis== | ==Prognosis== | ||
− | Good following complete surgical excision | + | *Good following complete surgical excision. |
− | + | *Recurrance following incomplete surgical excision is possible. | |
− | |||
− | |||
− | |||
− | |||
− | |||
==References== | ==References== | ||
− | Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA'' | + | *Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA'' |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | + | *Merck & Co (2008) '''The Merck Veterinary Manual''' | |
− | |||
− | |||
− |
Revision as of 10:14, 21 August 2009
This article is still under construction. |
Typical Signalment
- This is a common odontogenic tumour in cats.
- More rarely found in dogs.
Description
The lesions appear as masses that are friable and ulcerated. Many amyloid-producing odontogenic tumours are melanotic which makes them difficult to distinguish from the more aggressive malignant melanoma. They can erode but not infiltrate adjacent bone.
Diagnosis
Clinical Signs
- halitosis
- oral bleeding
- dental disruption or loss
- facial or mandibular deformity
- excessive salivation
- growth protruding from the mouth
- dysphagia occurs rarely
Diagnostic Imaging
Skull radiography may show a soft tissue opacity with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a dignostic possibility, thoracic radiography should be carried out to evaluate for lung metastases.
Biopsy
Required for a definitive diagnosis
- Incisional Biopsy - best
- Cytological or grab procedures - difficult to obtain a representative sample
Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated.
Treatment
- Surgical excision with narrow margins is normally sufficient.
- Radiation therapy should be considered in cases of incomplete surgical excision.
Prognosis
- Good following complete surgical excision.
- Recurrance following incomplete surgical excision is possible.
References
- Tutt, C., Deeprose, J. and Crossley, D. (2007) BSAVA Manual of Canine and Feline Dentistry (3rd Edition) BSAVA
- Merck & Co (2008) The Merck Veterinary Manual