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mLine 8:
Line 8: − These belong to the tetrahydropyrimidines class of drugs and a known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.+ − − ==Levamisole== − * This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on. − * It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase. − * It is a cholinergic agonist at neural and neuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it. − * It is rapidly absorbed and excreted and it's potency is related to it's peak plasma concentration. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations. − − ==Morantel== − +
Levamisole and Morantel moved to Morantel: They belong to different drug classes.
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It belongs to the tetrahydropyrimidines class of drugs, which are known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
* It has limited activity against larval forms and so has little uses.
* It has limited activity against larval forms and so has little uses.
* Morantel is used in some rumenal boluses.
* Morantel is used in some rumenal boluses.
* Pyrantel, a similar product, is used for against equine [[cestodes]].
* Pyrantel, a similar product, is used against equine [[cestodes]].