Difference between revisions of "Subcutaneous Mycoses"

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==Sporotrichosis==
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[[Sporotrichosis]]
[[Image:Sporotrichosis horse.jpg|thumb|right|150px|Sporotrichosis in a horse -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
 
[[Image:Sporotrichosis cigar cells.jpg|thumb|right|150px|Sporotrichosis cigar shaped cells -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
 
*''Sporothrix schenckii''
 
  
*Occurs in soil, wood and vegetation
 
**Saprophyte of both decaying and healthy vegetation
 
 
*Worldwide
 
 
*Exogenous infections through wounds
 
 
*Sporadic infections
 
 
*Non-contageous
 
 
*Causes subcutaneous nodules or granulomas
 
**Nodules ulcerate discharging pus
 
 
*Spread via the [[Lymphatic System - Anatomy & Physiology|lymphatics]]
 
 
*The [[Bones and Cartilage - Anatomy & Physiology|bones]] and viscera can be involved which terminates in mortality
 
**This is rare
 
**Reported in dogs and horses
 
 
*Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
 
**Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
 
**Can be confused with [[Subcutaneous Mycoses#Epizootic Lymphangitis|epizootic lymphangitis]] in horses
 
 
*Single cell, cigar shaped
 
**Usually found within [[Neutrophils - WikiBlood|neutrophils]]
 
**Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
 
 
*Stained using PAS, Gram stain (positive), fluorescent antibody and Calcofluor White
 
 
*Latex agglutination and immunodiffusion serology can be performed
 
 
*Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
 
**At 37°C:
 
***Colonies are smooth, cream to tan coloured and soft
 
***No mycelium can be seen
 
**At 25°C to 27°C:
 
***Colonies turn from white and soft to tan to brown to black
 
***Leathery, wrinkled and coarse
 
***Mycelium can be seen as branching septate hyphae
 
***Conidiospores can also be seen
 
 
*Potassium iodide treatment orally
 
**[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used
 
  
 
==Further Links==
 
==Further Links==

Revision as of 13:37, 29 April 2010