Difference between revisions of "Pasteurella multocida"

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(Created page with '*Large grey colonies on blood agar *Not haemolytic *Do not grow on MacConkey *Five capsular serotypes, A,B,D,E and F *Primary and secondary pathogen *Responsible for secondary in…')
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*Large grey colonies on blood agar
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==Introduction==
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*Not haemolytic
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''P.multocida'' is a very small, non-motile, gram-negative, ovoid, coccoid or short rod. It is aerobic and facultatively anaerobic species of the [[:Category:Pasteurella and Mannheimia species|''Pasteurella'']] genus. It forms large, grey colonies on blood agar and is not haemolytic. It does not grow on MacConkey. It has five capsular serotypes, A,B,D,E and F and can be a primary and secondary pathogen. It is responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Enzootic Pneumonia - Calves|Enzootic pneumonia of calves]] and pigs. It can cause [[Haemorrhagic_Disease_Pathophysiology#Vascular_Fragility|vascular fragility]], leading to haemorrhagic disease. It is also involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites. It causes [[Pasteurellosis - Rabbit|respiratory disease in rabbits]].
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*Do not grow on MacConkey
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*Five capsular serotypes, A,B,D,E and F
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*Primary and secondary pathogen
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*Responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]] and pigs
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* Can cause vascular fragility, leading to [[Haemostasis - Pathology#Haemorrhagic Disease Due To Vascular Fragility|haemorrhagic disease]]
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*Involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites
  
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==Type A==
 
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Type A is a commensal in the upper respiratory tract of animals in the UK. It is a primary pathogen in avian cholera - a septicaemia in chickens and turkeys. It is a secondary pathogen commonly responsible for dog and cat bite wound infections in humans and animals. It is also involved in feline pyothorax and cellulitis.
 
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Some strains are involved in [[Atrophic Rhinitis]] of pigs, and produce osteolytic toxin. It is also involved in [[Snuffles|snuffles]] in rabbits, a mucopurulent rhinosinusitis and can cause pneumonia and mastitis in sheep. In cattle it is associated with [[Pneumonic Pasteurellosis|pneumonic pasteurellosis]], as well as enzootic pneumonia in calves.
 
  
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==Type B==
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*Typa A
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Type B causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia.
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**Commensal in upper respiratory tract of animals in UK
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**Primary pathogen in avian cholera - a septicaemia in chickens and turkeys
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**Secondary pathogen commomly repsonsible for dog and cat bite wound infections in humans and animals
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**Feline pyothorax and [[Muscles Inflammatory - Pathology#Abscesses|cellulitis]]
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**Some strains involved in [[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis of pigs]], and produce osteolytic toxin
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**Involved in [[Respiratory Bacterial Infections - Pathology#In Rabbits|'Snuffles' in rabbits]], a mucopurulent rhinosinitis
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**Can cause pneumonia and mastitis in sheep
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**Associated with [[Respiratory Bacterial Infections - Pathology#Pneumonic pasteurellosis|pneumonic pasteurellosis]] in cattle, as well as enzootic pneumonia in calves
  
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==Type D==
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*Type B
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Type D is a primary and secondary pathogen. It causes [[Atrophic Rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs. ''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]'' and produce an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates.
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**Causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia
  
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==Type E==
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*Type D
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Type E causes African Bovine Haemorrhagic Septicaemia.
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**Primary and secondary pathogen
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**Causes [[Respiratory Bacterial Infections - Pathology#In Pigs|atrophic rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs
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**Pneumonia in pigs
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**''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]''
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**Produces an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates
  
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*Type E
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{{Learning
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**Causes African Bovine Haemorrhagic Septicaemia[[Category:Pasteurella and Mannheimia species]]
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|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Pasteurella+multocida%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=50&y=9 ''Pasteurella multocida'' publications since 2000]
 
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{{review}}
 
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{{OpenPages}}
 
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[[Category:Pasteurella and Mannheimia species]].
 
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[[Category:Expert_Review - Bacteria]]
 

Revision as of 12:21, 14 May 2010

  • Large grey colonies on blood agar
  • Not haemolytic
  • Do not grow on MacConkey
  • Five capsular serotypes, A,B,D,E and F
  • Primary and secondary pathogen
  • Responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during Enzootic pneumonia of calves and pigs
  • Can cause vascular fragility, leading to haemorrhagic disease
  • Involved in subcutaneous abscesses due to cat bites


  • Typa A
    • Commensal in upper respiratory tract of animals in UK
    • Primary pathogen in avian cholera - a septicaemia in chickens and turkeys
    • Secondary pathogen commomly repsonsible for dog and cat bite wound infections in humans and animals
    • Feline pyothorax and cellulitis
    • Some strains involved in Atrophic rhinitis of pigs, and produce osteolytic toxin
    • Involved in 'Snuffles' in rabbits, a mucopurulent rhinosinitis
    • Can cause pneumonia and mastitis in sheep
    • Associated with pneumonic pasteurellosis in cattle, as well as enzootic pneumonia in calves
  • Type B
    • Causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia
  • Type E
    • Causes African Bovine Haemorrhagic Septicaemia
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