Difference between revisions of "Bordetella bronchiseptica"
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| − | + | ===Infectious canine tracheitis/Kennel cough=== | |
| − | + | *''B. bronchiseptica'' acts as a primary pathogen in [[Respiratory Viral Infections - Pathology#Infectious canine tracheitis|Infectious canine tracheitis]] | |
| − | + | *Frequently isolated from dogs with respiratory disease | |
| − | | | + | *Often found with viruses or mycoplasma |
| − | | | + | *Adheres to ciliated epithelial cells in the trachea |
| − | | | + | *Colonisation and proliferation in trachea |
| − | + | *Releases toxins causing epithelial necrosis and prevents ciliary clearance | |
| − | + | *Irritation to tract causes coughing | |
| − | + | *Mortality rates low | |
| − | + | *Peribronchial inflammation and [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]] | |
| + | can result in unvaccinated puppies or immunosuppressed dogs | ||
| + | *Severe pneumonia following secondary infection e.g. with [[:Category:Streptococcus species|Streptococci]] | ||
| + | *Fatal [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]] if occurs secondary to [[Paramyxoviridae#Canine distemper virus|canine distemper virus]] | ||
| + | *Transmission via respiratory secretions by direct contact or aerosol and on fomites | ||
| + | *Clinical signs: | ||
| + | **Develop within 3-4 days; persist for up to 2 weeks | ||
| + | **Coughing | ||
| + | **Gagging | ||
| + | **Mild serous oculonasal discharge | ||
| + | *Treatments includes antibiotics if coughing persists or bronchopneumonia develops | ||
| + | *Live intranasal vaccines | ||
| + | *Also found in respiratory tract of cats; can cause pneumonia in kittens; vaccine available | ||
| − | + | ===Atrophic Rhinitis=== | |
| − | '' | + | *''B. bronchiseptica'' causes [[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis of pigs]] in association with [[Pasteurella multocida|''Pasteurella multocida'']] |
| − | + | *Colonises nasopharynx | |
| − | + | *Infection must occur during first few weeks of life | |
| − | + | *Produces dermonecrotic toxin which damages osteoblasts, preventing bone formation | |
| − | + | *Leads to turbinate atrophy without distortion of the snout in uncomplicated infections | |
| − | + | *[[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis]] results when [[Pasteurella multocida|''Pasteurella multocida'']] colonises and produces osteolytic toxin, leading to bone resorption | |
| − | + | *Malformation of snout in growing pigs as well as poor growth | |
| − | + | *increases with high stocking density and poor ventilation | |
| − | + | *Vaccine available | |
| − | + | [[Category:Bordetella species]][[Category:Dog]][[Category:Pig]] | |
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Revision as of 11:16, 17 May 2010
Infectious canine tracheitis/Kennel cough
- B. bronchiseptica acts as a primary pathogen in Infectious canine tracheitis
- Frequently isolated from dogs with respiratory disease
- Often found with viruses or mycoplasma
- Adheres to ciliated epithelial cells in the trachea
- Colonisation and proliferation in trachea
- Releases toxins causing epithelial necrosis and prevents ciliary clearance
- Irritation to tract causes coughing
- Mortality rates low
- Peribronchial inflammation and bronchopneumonia
can result in unvaccinated puppies or immunosuppressed dogs
- Severe pneumonia following secondary infection e.g. with Streptococci
- Fatal bronchopneumonia if occurs secondary to canine distemper virus
- Transmission via respiratory secretions by direct contact or aerosol and on fomites
- Clinical signs:
- Develop within 3-4 days; persist for up to 2 weeks
- Coughing
- Gagging
- Mild serous oculonasal discharge
- Treatments includes antibiotics if coughing persists or bronchopneumonia develops
- Live intranasal vaccines
- Also found in respiratory tract of cats; can cause pneumonia in kittens; vaccine available
Atrophic Rhinitis
- B. bronchiseptica causes Atrophic rhinitis of pigs in association with Pasteurella multocida
- Colonises nasopharynx
- Infection must occur during first few weeks of life
- Produces dermonecrotic toxin which damages osteoblasts, preventing bone formation
- Leads to turbinate atrophy without distortion of the snout in uncomplicated infections
- Atrophic rhinitis results when Pasteurella multocida colonises and produces osteolytic toxin, leading to bone resorption
- Malformation of snout in growing pigs as well as poor growth
- increases with high stocking density and poor ventilation
- Vaccine available