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| | }} | | }} |
| | <br> | | <br> |
| | + | **[[Respiratory Viral Infections - Pathology#Infectious bovine rhinotracheitis (IBR)|'''Infectious bovine rhinotracheitis (IBR)''']] |
| | | | |
| − | ====Antigenicity====
| + | ===Antigenicity=== |
| | *Two different viruses: | | *Two different viruses: |
| − | **[[Respiratory Viral Infections - Pathology#Infectious bovine rhinotracheitis (IBR)|'''Infectious bovine rhinotracheitis (IBR)''']]: aerosol transfer
| + | |
| − | **'''Infectrious Pustular Vulvovaginitis (IPV)''': venereal transfer
| + | [[Infectious Bovine Rhinotracheitis]] |
| | + | |
| | + | |
| | + | |
| | + | [[Infectious Pustular Vulvovaginitis]] |
| | + | |
| | + | Also known as IPV |
| | + | Caused by:[[Bovine Herpesvirus 1]] |
| | + | |
| | + | : venereal transfer |
| | | | |
| | ====Pathogenesis==== | | ====Pathogenesis==== |
| − | '''IBR''':
| |
| − | *BHV-1 infects the respiratory mucosal epithelial cells (intranuclear inclusion eosinophilic inclusion bodies)from nasal mucosa down to bronchioles
| |
| − | **Leading to neutrophilic inflammation of varying severity: serous -> catarrhal -> purulent nasal discharge, sneezing, coughing
| |
| − | *Dypsnoea, anorexia
| |
| − | *Rhinotracheitis that can develop into bronchopneumonia
| |
| − | *Clinical signs include coughing, discharge, lacrimation, and increased respiratory rate
| |
| − | *Clinical disease most severe in young calves - can develop mucosal ulcerative lesions in the oesophagus and forestomachs and viraemia with multiorgan infection
| |
| − | *Generally high morbidity, low mortality, but up to 75% mortality if concurrent with [[Bovine Virus Diarrhoea Virus|BVDV]], caused by meningo-encephalitis
| |
| | | | |
| − | '''IPV''':
| |
| | *Painful genital lesions | | *Painful genital lesions |
| | *Impaired reproductive performance | | *Impaired reproductive performance |
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| | ***ELISA for gE deletion can enable culling of carrier animals | | ***ELISA for gE deletion can enable culling of carrier animals |
| | *IPV has mostly been made obsolete by AI | | *IPV has mostly been made obsolete by AI |
| | + | [[Category:Herpesviridae]] |