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| | ==[[Intestinal Arterial Thromboembolism]] == | | ==[[Intestinal Arterial Thromboembolism]] == |
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| − | * Non-strangulation infarction.
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| − | * There is often a functional obstruction at point of infarction.
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| − | * Relatively rare as the bowel has a good anastomosing blood supply.
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| − | [[Image:strongylus vulgaris.jpg|thumb|right|150px|Thrombosis of cranial mesenteric artery caused by Strongylus vulgaris larvae (Courtesy of Bristol BioMed Image Archive)]]
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| − | ===Horses===
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| − | * E.g. [[Strongylus vulgaris|'''''Strongylus vulgaris''''']] larvae migrating in cranial mesenteric artery in horse
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| − | ** Cause arteritis with thickening of wall
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| − | *** Due to fibrin and debris deposition and hypersensitivity reaction
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| − | ** Leads to vasoconstriction
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| − | *** May occlude lumen and encourage thromboemboli.
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| − | ** Can cause ischaemic necrosis of a segment of [[Small Intestine - Anatomy & Physiology|small intestine]]
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| − | ** Is less common now that [[Strongylus vulgaris|'''''Strongylus vulgaris''''']] infections are declining.
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| − | * E.g. '''equine''' [[Intestines Fibrinous/Haemorrhagic Enteritis - Pathology#Salmonellosis|'''salmonellosis''']].
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| − | [[Image:Infaction of the small bowel.jpg|thumb|right|150px|Infarction of the small bowel (Courtesy of Bristol BioMed Image Archive)]]
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| − | ===Small Animals===
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| − | * Especially dogs
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| − | * '''Road traffic accidents''' produce and infact in the gut.
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| − | * '''Renal disease''' also causes infarction.
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| − | ** Particularly nephrotic syndrome.
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| − | ** Anticoagulant proteins are lost in the urine, leading to a prothrombic state in the ciruclation.
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| − | ===Pathology===
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| − | * Similar to that caused by venous congestion.
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| − | * See sharply delineated dark areas in bowel that are flaccid with loss of tone.
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| − | ** These become necrotic followed later by peritonitis.
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| | [[Category:Intestines,_Small_and_Large_-_Pathology]] | | [[Category:Intestines,_Small_and_Large_-_Pathology]] |
Revision as of 13:07, 1 June 2010
- Vascular disturbances cause obstruction of efferent veins, blockage of afferent arteries or reduced blood flow through unobstructed circulation.
- All have similar effects on the intestine
Effects of Intestinal Hypoxia
- Intestinal hypoxia is induced by vasular distrubances (above).
- Timescale:
- 10 – 30 minutes - separation of epithelium from basement membrane.
- 1 - 2 hours - villus destruction.
- 2 hours - necrosis of crypt cells.
- 4 - 5 hours - all mucosa necrotic, sloughed.
Pages in category "Intestine - Vascular Disturbances"
The following 2 pages are in this category, out of 2 total.