Difference between revisions of "Pancreatic Hypoplasia"
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| − | + | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine] | |
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| − | + | *Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats | |
| − | + | *Endocrine part of the pancreas seems unaffected | |
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| − | == | + | ===Clinical signs=== |
| − | + | *[[Exocrine Pancreatic Insufficiency]] | |
| − | + | *Occurs at about one year of age | |
| − | + | *Onset often preceded by another illness | |
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| − | + | ===Gross appearance=== | |
| + | *Pot-bellied appearance on external view | ||
| + | *Intestines are distended by bulky fatty ingesta | ||
| + | *Lack of fat in the mesentery and rest of the abdomen | ||
| + | *The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat | ||
| + | *The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size | ||
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| − | [[ | + | ===Microscopic appearance=== |
| − | [[Category: | + | *Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreas Degenerative - Pathology#Juvenile pancreatic atrophy|juvenile atrophy]] |
| + | *Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells | ||
| + | [[Category:Pancreas - Developmental Pathology]][[Category:Cattle]][[Category:Cat]][[Category:Dog]] | ||
Revision as of 12:32, 9 June 2010
Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine
- Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
- Endocrine part of the pancreas seems unaffected
Clinical signs
- Exocrine Pancreatic Insufficiency
- Occurs at about one year of age
- Onset often preceded by another illness
Gross appearance
- Pot-bellied appearance on external view
- Intestines are distended by bulky fatty ingesta
- Lack of fat in the mesentery and rest of the abdomen
- The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
- The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
Microscopic appearance
- Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the pancreas is normal at birth but undergoes progressive regression - juvenile atrophy
- Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells