Difference between revisions of "Immunoglobulin D"
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| − | [[Image:LH IgD.png|thumb| | + | <p>''Shortened to IgD''</p> |
| − | [[Image:IgD.jpg|thumb|right| | + | [[Image:LH IgD.png|thumb|150px|right|'''IgD''']] |
| − | + | [[Image:IgD.jpg|thumb|right|150px|IgD - B. Catchpole, RVC 2008]] | |
| − | + | <p>IgD is present in ruminants, pigs, (dogs) and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.</p> | |
| − | IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted. | ||
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==Structure== | ==Structure== | ||
| − | + | <p>IgD is Y-shaped and in rodents it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.</p> | |
| − | IgD is Y-shaped | ||
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==Function== | ==Function== | ||
| − | + | <p> | |
| − | IgD is only expressed in association with | + | *IgD is only expressed in association with IgM |
| − | <p> | + | *It is important in B-cell development. </p> |
| − | + | <br> | |
| − | + | ---- | |
| − | + | <center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D|Immunoglobulin D]], [[Immunoglobulin E - WikiBlood|Immunoglobulin E]], [[Immunoglobulin G|Immunoglobulin G]] & [[Immunoglobulin M|Immunoglobulin M]]</sup></b></center> | |
| − | [[Immunoglobulins|Immunoglobulins]] | ||
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| − | [[Immunoglobulin A|Immunoglobulin A]] | ||
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| − | [[Immunoglobulin E|Immunoglobulin E]] | ||
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| − | [[Immunoglobulin G|Immunoglobulin G]] | ||
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| − | [[Immunoglobulin M|Immunoglobulin M]] | ||
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Revision as of 16:26, 12 June 2010
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Shortened to IgD
IgD is present in ruminants, pigs, (dogs) and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.
Structure
IgD is Y-shaped and in rodents it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.
Function
- IgD is only expressed in association with IgM
- It is important in B-cell development.