Difference between revisions of "Brucellosis - Cattle"

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**Seminal vesicles, ampullae, testicles and epididymus infected in bulls; necrotising orchitis
 
**Seminal vesicles, ampullae, testicles and epididymus infected in bulls; necrotising orchitis
 
**Decreased fertility in cows and bulls; decreased milk production  
 
**Decreased fertility in cows and bulls; decreased milk production  
**Localisation in [[Spleen - Anatomy & Physiology|spleen]] and lymphatic tissue of non-pregnant animals
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**Occasionally causes [[Joints Inflammatory - Pathology#In Cattle|arthritis]]
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*Isolated from closed cases of [[Bursae and Tendons Inflammatory - Pathology#Poll Evil and Fistulous Withers|poll evil and fistulous withers]] in horses
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Vaccination of heifers against ''B. abortus'' in endemic regions by Strain S19, a live attenuated vaccine, stimulating a cell-mediated immune response. The vaccination of young animals interferes with serological testing. The 45/20 bacterin vaccine is less effective and the newer RB51 vaccine has no LPS O-antigen therefore not detected by serological tests and gives good protection.
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[[Category:To_Do_-_Clinical]]
 
[[Category:To_Do_-_Clinical]]

Revision as of 15:14, 23 July 2010



    • Caused by Brucella abortus
    • Eradicated in many countries including UK
    • Infection usually by ingestions but also venereal, skin abrasions, inhalation, transplacental
    • Abortion storms in susceptible herds
    • Abortion after fifth month of gestation due to placentitis
    • Brucellae excreted in foetal fluids for 2-4 weeks following abortion and at subsequent parturitions without abortion
    • Infection of mammary glands and lymph nodes persists for years
    • Excreted intermittently in milk for years
    • Seminal vesicles, ampullae, testicles and epididymus infected in bulls; necrotising orchitis
    • Decreased fertility in cows and bulls; decreased milk production


Vaccination of heifers against B. abortus in endemic regions by Strain S19, a live attenuated vaccine, stimulating a cell-mediated immune response. The vaccination of young animals interferes with serological testing. The 45/20 bacterin vaccine is less effective and the newer RB51 vaccine has no LPS O-antigen therefore not detected by serological tests and gives good protection.