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| | | |
| {| cellpadding="10" cellspacing="0" border="1" | | {| cellpadding="10" cellspacing="0" border="1" |
− | | Also known as: | + | |Also known as: |
− | | '''Senecio jacobea<br> | + | |'''Senecio jacobea<br> |
| |-} | | |-} |
| + | |
| + | ==Description== |
| + | |
| + | ==Signalment== |
| + | |
| + | ==Diagnosis== |
| + | |
| + | ===Clinical signs=== |
| + | |
| + | ===Cytology=== |
| + | |
| + | ===Biopsy=== |
| + | |
| + | ==Treatment== |
| + | |
| + | ==Prognosis== |
| + | |
| + | ==References== |
| + | * Knottenbelt, D.C. '''A Handbook of Equine Medicine for Final Year Students''' ''University of Liverpool'' |
| + | *Rose, R. J. and Hodgson, D. R. (2000) '''Manual of Equine Practice''' (Second Edition) Sauders. |
| + | |
| | | |
| ==Hepatotoxicity== | | ==Hepatotoxicity== |
− | *plant toxin ingested over a long period of time
| + | plant toxin ingested over a long period of time |
| *livestock | | *livestock |
| **cattle and horses are more susceptible than sheep | | **cattle and horses are more susceptible than sheep |
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| *it is likely that the vascular component of the attempted repair of the chronic damage by fibrosis (really a type of granulation tissue) aids the shunting from the portal triads to the central vein and thereby bypassing the hepatocytes | | *it is likely that the vascular component of the attempted repair of the chronic damage by fibrosis (really a type of granulation tissue) aids the shunting from the portal triads to the central vein and thereby bypassing the hepatocytes |
| *other plant and fungal toxins perform in the same way | | *other plant and fungal toxins perform in the same way |
| + | |
| ====Gross==== | | ====Gross==== |
| *slightly enlarged [[Liver - Anatomy & Physiology|liver]] | | *slightly enlarged [[Liver - Anatomy & Physiology|liver]] |
| *pale in colour | | *pale in colour |
| *very firm to section | | *very firm to section |
| + | |
| ====Microscopically==== | | ====Microscopically==== |
| *necrosis | | *necrosis |
| *haemorrhage | | *haemorrhage |
| *diffuse fibrosis | | *diffuse fibrosis |
| + | |
| | | |
| [[Category:Hepatotoxicity, Chronic]][[Category:Horse]][[Category:Sheep]] | | [[Category:Hepatotoxicity, Chronic]][[Category:Horse]][[Category:Sheep]] |
| [[Category:To_Do_- lizzyk]] | | [[Category:To_Do_- lizzyk]] |