Difference between revisions of "Intestinal Arterial Thromboembolism"

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** Leads to vasoconstriction  
 
** Leads to vasoconstriction  
 
*** May occlude lumen and encourage thromboemboli.  
 
*** May occlude lumen and encourage thromboemboli.  
** Can cause ischaemic necrosis of a segment of [[Small Intestine Overview - Anatomy & Physiology|small intestine]]
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** Can cause ischaemic necrosis of a segment of [[Small Intestine - Anatomy & Physiology|small intestine]]
 
** Is less common now that [[Strongylus vulgaris|'''''Strongylus vulgaris''''']]  infections are declining.
 
** Is less common now that [[Strongylus vulgaris|'''''Strongylus vulgaris''''']]  infections are declining.
 
* E.g. '''equine''' [[Salmonellosis|'''salmonellosis''']].
 
* E.g. '''equine''' [[Salmonellosis|'''salmonellosis''']].
 
[[Image:Infaction of the small bowel.jpg|thumb|right|150px|Infarction of the small bowel (Courtesy of Bristol BioMed Image Archive)]]
 
[[Image:Infaction of the small bowel.jpg|thumb|right|150px|Infarction of the small bowel (Courtesy of Bristol BioMed Image Archive)]]
==== Verminous endarteritis ====
 
*Caused by larvae of [[Strongylus vulgaris|''S. vulgaris'']] within the cranial mesenteric artery
 
*Also called "verminous aneurism" (misnomer as aneurism = dilatation/thinning of blood vessel wall; also, aneurisms are rare)
 
*Wall of artery grossly thickened (organising thrombi, inflammatory responses)
 
*Can be detected on rectal palpation
 
*Many cases asymptomatic
 
*May get embolism → infarction of areas of intestinal wall → colic or chronic ulceration (note: generally good collateral circulation; therefore colic is not inevitable)
 
*Aberrant larvae may cause thrombosis in other arteries; e.g. iliac, cerebral, coronary
 
*Avermectin/milbemycins or fenbendazole are used to control migrating ''S. vulgaris'' larvae
 
 
  
 
===Small Animals===
 
===Small Animals===
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* Similar to that caused by venous congestion.
 
* Similar to that caused by venous congestion.
 
* See sharply delineated dark areas in bowel that are flaccid with loss of tone.   
 
* See sharply delineated dark areas in bowel that are flaccid with loss of tone.   
** These become necrotic followed later by peritonitis.
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** These become necrotic followed later by peritonitis.[[Category:Intestine_-_Vascular_Disturbances]]
 
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[[Category:Dog]][[Category:Cat]]
 
 
[[Category:Intestine_-_Vascular_Disturbances]]
 
[[Category:Intestinal Diseases - Dog]][[Category:Vascular Diseases - Dog]][[Category:Intestinal Diseases - Cat]][[Category:Vascular Diseases - Cat]]
 
 
[[Category:To_Do_-_Clinical]]
 
[[Category:To_Do_-_Clinical]]
[[Category:Vascular Diseases - Horse]]
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[[Category:Cardiovascular_Disorders_-_Horse]]
[[Category:Small Intestinal Diseases - Horse]]
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[[Category:Small_Intestinal_Disorders_-_Horse]]
[[Category:Cardiology Section]]
 

Revision as of 13:30, 30 July 2010

  • Non-strangulation infarction.
  • There is often a functional obstruction at point of infarction.
  • Relatively rare as the bowel has a good anastomosing blood supply.
Thrombosis of cranial mesenteric artery caused by Strongylus vulgaris larvae (Courtesy of Bristol BioMed Image Archive)

Horses

  • E.g. Strongylus vulgaris larvae migrating in cranial mesenteric artery in horse
    • Cause arteritis with thickening of wall
      • Due to fibrin and debris deposition and hypersensitivity reaction
    • Leads to vasoconstriction
      • May occlude lumen and encourage thromboemboli.
    • Can cause ischaemic necrosis of a segment of small intestine
    • Is less common now that Strongylus vulgaris infections are declining.
  • E.g. equine salmonellosis.
Infarction of the small bowel (Courtesy of Bristol BioMed Image Archive)

Small Animals

  • Especially dogs
  • Road traffic accidents produce and infact in the gut.
  • Renal disease also causes infarction.
    • Particularly nephrotic syndrome.
    • Anticoagulant proteins are lost in the urine, leading to a prothrombic state in the ciruclation.

Pathology

  • Similar to that caused by venous congestion.
  • See sharply delineated dark areas in bowel that are flaccid with loss of tone.
    • These become necrotic followed later by peritonitis.