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| + | * Eosinopenia is a reduction in the number of eosinophils in the blood. |
− | ==Introduction==
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− | Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]]. It ocurs most commonly as part of a [[Stress Leucogram|stress leucocgram]] and in other situations that result in an increase in the circulating concentration of glucocorticoids:
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− | *'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected. | + | * Occurs as part of the response to corticosteroids;. |
− | *'''[[Hyperadrenocorticism]]''' (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids. | + | ** Thought to be associated with the depressive effect of corticosteroids on lymphocytes. |
− | *'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.
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− | | + | *** Secretions of these lymphocytes are thought to stimulate eosinophil production. |
− | Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production.
| + | [[Category:Blood Cell Changes]][[Category:To Do - Blood]] |
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− | {{Learning
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− | |literature search = [http://www.cabdirect.org/search.html?q=title:(Eosinopenia)+OR+title:(Eosinopaenia)&fq=sc:%22ve%22 Eosinopenia specific publications]
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− | [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Eosinopenia&occuring1=ab&rowId=2&options2=OR&q2=Eosinopaenia&occuring2=ab&rowId=3&options3=AND&q3=&occuring3=freetext&x=33&y=11&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Eosinopaenia mentioned in abstract of publications]
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− | {{review}}
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− | [[Category:Haematology Changes]][[Category:Expert Review]] | |