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| Variable | | Variable |
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− | =Pathology= | + | ==Pathology== |
− | ===Introduction===
| + | |
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| * Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea. | | * Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea. |
| * The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected. | | * The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected. |
| ** The site determines whether diarrhoea is present. | | ** The site determines whether diarrhoea is present. |
− | * Additionally, can get extraintestinal abnormalities
| + | Additionally, can get extraintestinal abnormalities including cholangiohepatitis, nephritis, pancreatitis, polyarthropathy and thrombocytopenia (uncommon). |
− | ** Cholangiohepatitis
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− | ** Nephritis
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− | ** Pancreatitis
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− | ** Polyarthropathy
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− | ** Thrombocytopenia (uncommon)
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− | *** Extent of thrombocytopenia not related to duration of IBD or to its resolution.
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− | * The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present.
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− | ** All have some common features:
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− | *** Thickening of the mucosa.
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− | *** Villus atrophy in advanced disease.
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− | *** Significant inflammatory infiltrate in the mucosa and sometimes deeper layers.
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| | | |
| + | The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present. All have some common features: thickening of the mucosa, villus atrophy in advanced disease and significant inflammatory infiltrate in the mucosa and sometimes deeper layers. |
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| + | |
| ==Granulomatous enteritis== | | ==Granulomatous enteritis== |
| | | |
− | * Seen mainly in the dog.
| + | Is seen mainly in the dog but also in the cat and horse. It is idiopathic but causes granulomatous inflammation. |
− | ** Also in the cat and horse
| + | Macrophages, giant cells, [[Neutrophils|neutrophils]], eosinophils, lymphocytes and plasma cells are present. |
− | * Idiopathic.
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− | * Granulomatous inflammation
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− | ** Macrophages and giant cells, but also [[Neutrophils|neutrophils]], eosinophils, lymphocytes and plasma cells.
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| ==Idiopathic colitis== | | ==Idiopathic colitis== |