Difference between revisions of "Amyloid-producing Odontogenic Tumour"

Revision as of 08:50, 5 August 2010

Description

The lesions appear as masses that are friable and ulcerated. Many amyloid-producing odontogenic tumours are melanotic which makes them difficult to distinguish from the more aggressive malignant melanoma. They can erode but not infiltrate adjacent bone.

Typical Signalment

This is a common odontogenic tumour in cats and more rarely found in dogs.

Diagnosis

Clinical Signs

Include halitosis, oral bleeding, dental disruption or loss, facial or mandibular deformity, excessive salivation, growth protruding from the mouth and rarely dysphagia.

Diagnostic Imaging

Skull radiography may show a soft tissue opacity with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a dignostic possibility, thoracic radiography should be carried out to evaluate for lung metastases.

Biopsy

Required for a definitive diagnosis

Incisional Biopsy - best
Cytological or grab procedures - difficult to obtain a representative sample

Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated.

Treatment

Surgical excision with narrow margins is normally sufficient.
Radiation therapy should be considered in cases of incomplete surgical excision.

Prognosis

Good following complete surgical excision.
Recurrance following incomplete surgical excision is possible.

References

Tutt, C., Deeprose, J. and Crossley, D. (2007) BSAVA Manual of Canine and Feline Dentistry (3rd Edition) BSAVA

Merck & Co (2008) The Merck Veterinary Manual

@@ Line 1: / Line 1: @@
-{{OpenPagesTop}}
+{{unfinished}}
-Also known as: '''''Calcifying epithelial odontogenic tumour
-==Introduction==
+==Description==
-The lesions are slow growing and locally invasive.The most prominent feature of this type of tumour is that it produces amyloid which tends to calcify.
+The lesions appear as masses that are friable and ulcerated. Many amyloid-producing odontogenic tumours are [[Neoplasia - Pathology#Nomenclature|melanotic]] which makes them difficult to distinguish from the more aggressive malignant melanoma. They can erode but not infiltrate adjacent bone.
 ==Typical Signalment==
-This is a rare tumour seen more often in cats and than in dogs.
+This is a common odontogenic tumour in cats and more rarely found in dogs.
 ==Diagnosis==
 ===Clinical Signs===
 Include halitosis, oral bleeding, dental disruption or loss, facial or mandibular deformity, excessive salivation, growth protruding from the mouth and rarely dysphagia.
 ===Diagnostic Imaging===
-Skull radiography may show a soft tissue opacity  with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a diagnostic possibility, thoracic radiography should be carried out to evaluate for lung metastases.
+Skull radiography may show a soft tissue opacity  with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a dignostic possibility, thoracic radiography should be carried out to evaluate for lung metastases.
+===Biopsy===
-===Biopsy===
+Required for a definitive diagnosis
-Biopsy is required for a definitive diagnosis.
+*Incisional Biopsy - best
-Incisional biopsy is the best option, when undertaking cytological or grab procedures it is difficult to obtain a representative sample.
+*Cytological or grab procedures - difficult to obtain a representative sample
 Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated.
 ==Treatment==
-Surgical excision with narrow margins is normally sufficient.
+*Surgical excision with narrow margins is normally sufficient.
-Radiation therapy should be considered in cases of incomplete surgical excision.
+*Radiation therapy should be considered in cases of incomplete surgical excision.
 ==Prognosis==
-Good following complete surgical excision however recurrance following incomplete surgical excision is possible.
+*Good following complete surgical excision.
+*Recurrance following incomplete surgical excision is possible.
-{{Learning
-|literature search = [http://www.cabdirect.org/search.html?q=%28%28%28%22Amyloid+producing+Odontogenic+Tumor%22%29+OR+%28%22Calcifying+epithelial+odontogenic+tumor%22+%29%29%29+OR+%28%28%28%22Amyloid+producing+Odontogenic+Tumour%22%29+OR+%28%22Calcifying+epithelial+odontogenic+tumour%22+%29%29%29 Amyloid-producing Odontogenic Tumour publications]
-|Vetstream = [https://www.vetstream.com/felis/Content/Disease/dis02424.asp Amyloidosis]
-}}
 ==References==
-Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''
+*Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''
-Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''
-{{review}}
-{{OpenPages}}
-[[Category:Oral Diseases - Cat]][[Category:Oral_Cavity_-_Proliferative_Pathology]][[Category:Teeth_-_Proliferative_Pathology]]
+*Merck & Co (2008) '''The Merck Veterinary Manual'''
+[[Category:Cat]][[Category:Oral_Cavity_-_Proliferative_Pathology]][[Category:Teeth_-_Proliferative_Pathology]]
+[[Category:To_Do_-_Caz]]
 [[Category:Neoplasia]]
-[[Category:Oral Diseases - Dog]]
-[[Category:Expert Review - Small Animal]]
-[[Category:Oral Proliferations]]
-[[Category:LisaM reviewing]]