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Canine Leukocyte Adhesion Deficiency (view source)
Revision as of 13:49, 12 August 2010
, 13:49, 12 August 2010Created page with "(CLAD) *Occurs in Irish Setters *Missence mutation of -Cys-36-Ser- in CD18 molecule **CD18 is required for neutrophil migration and phagocytosis *Recurrent bacter..."
(CLAD)
*Occurs in Irish Setters
*Missence mutation of -Cys-36-Ser- in CD18 molecule
**CD18 is required for [[Neutrophils|neutrophil]] migration and phagocytosis
*Recurrent bacterial infection
*Neutrophilia ([[Neutrophils|neutrophils]] remain in the blood and are unable to fight infection in the tissue)
[[Category:Primary Innate Immunity Deficiencies]]
[[Category:To Do - Blood]]
*Occurs in Irish Setters
*Missence mutation of -Cys-36-Ser- in CD18 molecule
**CD18 is required for [[Neutrophils|neutrophil]] migration and phagocytosis
*Recurrent bacterial infection
*Neutrophilia ([[Neutrophils|neutrophils]] remain in the blood and are unable to fight infection in the tissue)
[[Category:Primary Innate Immunity Deficiencies]]
[[Category:To Do - Blood]]