Difference between revisions of "Lymphocytosis"

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==Introduction==
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==Description==
 
Lymphocytosis refers to an increase in the number of circulating lymphocytes in the blood.  The major causes of lymphocytosis are:
 
Lymphocytosis refers to an increase in the number of circulating lymphocytes in the blood.  The major causes of lymphocytosis are:
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*Several types of '''neoplasia''' may result in increases in the number of blood lymphocytes, including:
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*Neoplasia
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**Stage V (leukaemic) [[Lymphoma|lymphoma]]
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**Several types of tumour may result in increases in the number of blood lymphocytes, including:
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**Acute lymphoblastic and chronic lymphocytic leukaemia
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***Stage V [[Lymphoma|lymphoma]]
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**Bovine Leukosis caused by [[Bovine Leukaemia Virus|bovine leukaemia virus (BoLV)]]
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***Acute lymphoblastic and chronic lymphocytic leukaemia
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*'''Stress''' may result in the release of lymphocytes into the circulation, especially in young horses and cats. This response is mediated by the release of adrenaline from the adrenal medulla and it should not be confused with the [[Stress Leucogram|stress leucogram]] produced by the release of the glucocorticoid hormones cortisol from the adrenal cortex. 
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***Bovine Leukosis caused by bovine leukaemia virus
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*Some cases of '''chronic infection''' may be associated with lymphocytosis but reactive hyperplasia in associated lymph nodes may not correlate with the numbers of circulating lymphocytes.
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*Stress
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*'''Physiological''' lymphocytosis is common in young animals of many species. In growing pigs, this may be associated with [[Mycoplasmas species - Overview|''Mycoplasma'']] infection.
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** Following adrenaline release in fear, excitement and so on.
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*In '''premature''' or '''dysmature equine neonates''', the normal neutrophil: lymphocyte ratio of approximately 2: 1 may be reversed to produce an apparent lymphocytosis.  Such animals will also have an increased mean corpuscular volume (MCV) of their red blood cells.
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*Chronic infection
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*'''Hypoadrenocorticism''' may result in lymphocytosis and/or [[Eosinophilia|eosinophilia]].
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** In some cases of chronic infection.
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*** However, reactive hyperplasia in associated lymph nodes may not correlate with the numbers of circulating lymphocytes.
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*Physiological
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** Commonly in growing swine.
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|literature search = [http://www.cabdirect.org/search.html?it=any&q1=lymphocytosis&calendarInput=yyyy-mm-dd&occuring1=title&rowId=1&rowId=2&rowId=3&show=all&options1=AND&options2=AND&options3=AND&occuring3=freetext&occuring2=freetext&publishedend=yyyy&la=any&publishedstart=yyyy&fq=sc%3A%22ve%22&y=14&x=37 Lymphocytosis publications]
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*** Possibly associated with aMycoplasma infection.
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*Equine neonates
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[[Category:Haematology Changes]][[Category:Expert Review]][[Category:Bullet Points]]
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[[Category:Blood Cell Changes]][[Category:To Do - James]]

Revision as of 19:34, 18 August 2010


 This article is still under construction.


Description

Lymphocytosis refers to an increase in the number of circulating lymphocytes in the blood. The major causes of lymphocytosis are:

  • Neoplasia
    • Several types of tumour may result in increases in the number of blood lymphocytes, including:
      • Stage V lymphoma
      • Acute lymphoblastic and chronic lymphocytic leukaemia
      • Bovine Leukosis caused by bovine leukaemia virus
  • Stress
    • Following adrenaline release in fear, excitement and so on.
  • Chronic infection
    • In some cases of chronic infection.
      • However, reactive hyperplasia in associated lymph nodes may not correlate with the numbers of circulating lymphocytes.
  • Physiological
    • Commonly in growing swine.
      • Possibly associated with aMycoplasma infection.
  • Equine neonates
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