Difference between revisions of "Lymphopenia"

Revision as of 10:42, 20 August 2010

Lymphopenia is a redcution in the numbers of lymphocytes in the blood.

Occurs in:
- Viruses that attack the lymphoid system.
  - For example:
    - Canine Distemper
    - Infectious Canine Hepatitis
    - Feline Infectious Enteritis
    - Bovine Virus Diarrhoea.
- Irradiation
- Corticosteroid therapy.
  - Selectively suppresses lymphocytic activity, and the inflammatory response in general.

- - Other immunosuppressive drugs may act in a similar way.

@@ Line 1: / Line 1: @@
+* Lymphopenia is a redcution in the numbers of lymphocytes in the blood.
-==Introduction==
+* Occurs in:
-Lymphopenia is a reduction in the numbers of lymphocytes in the blood.  This phenomenon is most commonly associated with stress (as part of the '''stress leucogram''') or with viral infection.  Causes include:
+** Viruses that attack the lymphoid system.
-*[[Stress Leucogram|Stress leucogram]], characterised by '''[[Neutrophilia|neutrophilia]]''', '''[[Monocytosis|monocytosis]]''', '''[[Eosinopenia|eosinopenia]]''' and '''[[Lymphopenia|lymphopenia]]'''.  A similar pattern may occur with hyperadrenocorticism (Cushing’s disease) or exogenous corticosteroid therapy as these hormones selectively suppress lymphocytic activity and the inflammatory response in general.
+*** For example:
-*Viral infection with [[Canine Distemper Virus|canine distemper]], [[Infectious Canine Hepatitis|Infectious canine hepatitis]], [[Feline infectious enteritis|feline infectious enteritis]] or [[Bovine Viral Diarrhoea|bovine viral diarrhoea]] (BVD)
+**** [[Paramyxoviridae#Canine Distemper Virus (CDV)|Canine Distemper]]
-*Bone marrow suppression caused by '''chemotherapy''' or '''radiotherapy'''.  Since neutrophils have a much shorter circulating half life, they are the first cell line to fall with any insult to the bone marrow but lymphopenia may occur as part of a more severe pancytopenia.
+**** Infectious Canine Hepatitis
-*Inherited or acquired immunodeficiency syndromes, including '''[[Equine Severe Combined Immune Deficiency|SCID]]''' (Severe Combined Immunodeficiency Syndrome) in Arab foals and [[Feline Immunodeficiency Virus|'''feline immunodeficiency virus''']] infection.
+**** Feline Infectious Enteritis
-*Leakage of lymphatic fluid may result in loss of lymphocytes, as occurs with '''[[Lymphangiectasia|lymphangiectasia]]''' or '''[[Chylous Effusion|chylothorax]]'''.
+**** Bovine Virus Diarrhoea.
+** Irradiation
+** Corticosteroid therapy.
+*** Selectively suppresses lymphocytic activity, and the inflammatory response in general.
-{{Learning
+*** Other immunosuppressive drugs may act in a similar way.
-|literature search = [http://www.cabdirect.org/search.html?it=any&q2=lymphopaenia&q1=lymphopenia&calendarInput=yyyy-mm-dd&occuring1=title&show=all&rowId=1&rowId=2&rowId=3&options1=AND&options2=OR&options3=AND&occuring3=freetext&occuring2=title&publishedend=yyyy&la=any&publishedstart=yyyy&fq=sc%3A%22ve%22&y=6&x=40 Publications with 'lymphopenia' in their title]
-}}
+[[Category:Haematology Changes]][[Category:To Do - James]]
-{{review}}
-==Webinars==
-<rss max="10" highlight="none">https://www.thewebinarvet.com/clinical-pathology/webinars/feed</rss>
-[[Category:Haematology Changes]][[Category:Expert Review]][[Category:Bullet Points]]

Difference between revisions of "Lymphopenia"

Revision as of 10:42, 20 August 2010

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