Below are common changes of numbers of blood cells during disease. Plasma cells are rarely found within blood. If many plasma cells are present in blood, it is due to a plasma cell tumour that has begun to metastasise.
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The essential blood film: quality control and so much more! Allison, R. W.; The North American Veterinary Conference, Gainesville, USA, Small animal and exotics. Proceedings of the North American Veterinary Conference, Orlando, Florida, USA, 17-21 January, 2009, 2009, pp 523-526 - Full Text Article