Difference between revisions of "Canine X-Linked Severe Combined Immune Deficiency"
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m (Text replace - "Category:Immune Diseases - Dog" to "Category:Immunological Diseases - Dog") |
m (Text replace - "Category:To Do - Blood" to "Category:To Do - BloodCategory:To Do - Clinical") |
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*Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection | *Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection | ||
*Animal usually dies from pneumonia or sepsis as the level of maternal [[Immunoglobulins|antibody]] decreases | *Animal usually dies from pneumonia or sepsis as the level of maternal [[Immunoglobulins|antibody]] decreases | ||
| − | [[Category:Primary Adaptive Immunity Deficiencies]][[Category: | + | [[Category:Primary Adaptive Immunity Deficiencies]][[Category:Dog]] |
[[Category:To Do - Blood]][[Category:To Do - Clinical]] | [[Category:To Do - Blood]][[Category:To Do - Clinical]] | ||
Revision as of 10:52, 20 August 2010
(Canine SCID)
- Affects Basset Hounds and Corgis
- X-linked recessive defect in the gene coding for the IL-2 receptor
- IL-2 receptor is a receptor for the cytokine IL-2 which causes T cells to proliferate
- Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection
- Animal usually dies from pneumonia or sepsis as the level of maternal antibody decreases