Difference between revisions of "Adrenogenital Syndrome"
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+ | {{toplink | ||
+ | |backcolour =EED2EE | ||
+ | |linkpage =Reproductive System - Anatomy & Physiology | ||
+ | |linktext =Reproductive System | ||
+ | |maplink = Reproductive System (Content Map) - Anatomy & Physiology | ||
+ | |sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development | ||
+ | |subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT | ||
+ | |sublink2=Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation- Anatomy & Physiology | ||
+ | |subtext2=SEXUAL DIFFERENTIATION | ||
+ | }} | ||
+ | <br> | ||
== Aetiology == | == Aetiology == | ||
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* Genotype is XX as should be female | * Genotype is XX as should be female | ||
* Ovaries develop normally | * Ovaries develop normally | ||
− | * Foetal [[Adrenal_Glands_- | + | * Foetal [[Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''. |
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− | [[Category:Reproductive | + | [[Category:Reproductive System]] |
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Revision as of 15:06, 22 August 2010
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Aetiology
- Genotype is XX as should be female
- Ovaries develop normally
- Foetal Adrenal Gland is hyperactive and secretes large quantities of Adrenal Androgens, due to a 21 hydroxylase mutation.
Consequence
- Wolffian Ducts persist due to the presence of Androgens, thus allowing development of male internal and external genitalia.
- Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of female internal genitalia.
Morphology
- Appears male with a micropenis and scrotum
- Both male and female internal genitalia