Difference between revisions of "Gut Endocrine Function - Anatomy & Physiology"
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Various regions of the [[Alimentary System Overview - Anatomy & Physiology|Alimentary Tract]] secrete [[Hormones - Anatomy & Physiology|hormones]] which have various functions within the gastrointestinal tract itself, plus the [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]] and [[Pancreas - Anatomy & Physiology| | Various regions of the [[Alimentary System Overview - Anatomy & Physiology|Alimentary Tract]] secrete [[Hormones - Anatomy & Physiology|hormones]] which have various functions within the gastrointestinal tract itself, plus the [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]] and [[Pancreas - Anatomy & Physiology| | ||
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|<font color=Purple>Gastrin</font> | |<font color=Purple>Gastrin</font> | ||
| − | |G-Cells in [[ | + | |G-Cells in [[Forestomach - Anatomy & Physiology|stomach]] and [[Duodenum - Anatomy & Physiology|duodenum]] |
| − | |Stimulates Parietal cells in the [[ | + | |Stimulates Parietal cells in the [[Forestomach - Anatomy & Physiology|stomach]] to secrete HCl and Chief cells to secrete pepsinogen. |
|- | |- | ||
|<font color=Purple>Gastric Inhibitory Peptide</font> | |<font color=Purple>Gastric Inhibitory Peptide</font> | ||
|[[Duodenum - Anatomy & Physiology|Duodenum]]and [[Jejunum - Anatomy & Physiology|Jejunum]] | |[[Duodenum - Anatomy & Physiology|Duodenum]]and [[Jejunum - Anatomy & Physiology|Jejunum]] | ||
| − | |Inhibits gastric motility and HCl secretion in the [[ | + | |Inhibits gastric motility and HCl secretion in the [[Forestomach - Anatomy & Physiology|stomach]], induces insulin secretion. |
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|<font color=Purple>Ghrelin</font> | |<font color=Purple>Ghrelin</font> | ||
| − | |[[ | + | |[[Forestomach - Anatomy & Physiology|Stomach]] and [[Pancreas - Anatomy & Physiology|Pancreas]] |
|Increases food intake (by stimulating hunger) at the level of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]]. | |Increases food intake (by stimulating hunger) at the level of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]]. | ||
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|<font color=Purple>Secretin</font> | |<font color=Purple>Secretin</font> | ||
|Crypts of Leiberkuhn in the [[Duodenum - Anatomy & Physiology|Duodenum]] | |Crypts of Leiberkuhn in the [[Duodenum - Anatomy & Physiology|Duodenum]] | ||
| − | |Causes secretion of bicarbonate to buffer the pH of the chyme entering the [[Small Intestine | + | |Causes secretion of bicarbonate to buffer the pH of the chyme entering the [[Small Intestine - Anatomy & Physiology|small intestine]]. Also triggers insulin release. |
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|<font color=Purple>Somatostatin </font> | |<font color=Purple>Somatostatin </font> | ||
| − | |Gastric glands of the [[ | + | |Gastric glands of the [[Forestomach - Anatomy & Physiology|stomach]] |
| − | |Inhibits release of gastrin and HCl from the [[ | + | |Inhibits release of gastrin and HCl from the [[Forestomach - Anatomy & Physiology|stomach]], inhibits secretin and cholecystokinin release from the [[Duodenum - Anatomy & Physiology|duodenum]] and inhibits release of glucagon from the [[Pancreas - Anatomy & Physiology|pancreas]]. |
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| − | + | [[Category:Endocrine System]] | |
| − | [[Category:Endocrine System | ||
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Revision as of 15:28, 31 August 2010
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Various regions of the Alimentary Tract secrete hormones which have various functions within the gastrointestinal tract itself, plus the liver, gall bladder and pancreas.
Many of the hormones act in a paracrine fashion, exerting their effect on cells close to the secretion site without travelling in the bloodstream.
| Hormone | Site of Secretion within GIT | Action |
|---|---|---|
| Cholecystokinin | Duodenum | Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the pancreas and gall bladder. |
| Gastrin | G-Cells in stomach and duodenum | Stimulates Parietal cells in the stomach to secrete HCl and Chief cells to secrete pepsinogen. |
| Gastric Inhibitory Peptide | Duodenumand Jejunum | Inhibits gastric motility and HCl secretion in the stomach, induces insulin secretion. |
| Ghrelin | Stomach and Pancreas | Increases food intake (by stimulating hunger) at the level of the hypothalamus. |
| Secretin | Crypts of Leiberkuhn in the Duodenum | Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release. |
| Somatostatin | Gastric glands of the stomach | Inhibits release of gastrin and HCl from the stomach, inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the pancreas. |