Difference between revisions of "Sjorgren’s-like syndrome"

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*Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]].
== Introduction ==
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*Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively.
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*May be primary autoimmune or part of another autoimmune condition.
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*Causes of xerostomia:
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**Dysautonomia
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**Infectious sialadenitis
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**Neoplasia
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**Salivary amyloidosis
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**Head and neck radiation
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**Drugs
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**AutoI disease.
  
This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.
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'''Tagging-PG'''
  
Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.
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[[Category:Salivary Glands - Pathology]]
 
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[[Category:To_Do_-_Clinical]]
 
 
== Clinical Signs ==
 
 
 
Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[Periodontal Disease|gingivitis]] and [[glossitis]] are all possible clinical signs.
 
 
 
 
 
== Diagnosis ==
 
 
 
Diagnosis by elimination of all other causes of these clinical signs.
 
 
 
 
 
== Treatment ==
 
 
 
None
 
 
 
Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.
 
 
 
 
 
== Prognosis ==
 
 
 
Guarded to Poor
 
 
 
 
 
{{Learning
 
|Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis60223.asp Sjogren's-like syndrome]
 
}}
 
 
 
== References ==
 
 
 
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial
 
 
 
Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.
 
 
 
Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins.
 
 
 
 
 
{{review}}
 
 
 
{{OpenPages}}
 
 
 
[[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]]
 

Revision as of 16:16, 4 September 2010

  • Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of salivary glands.
  • Both those terms refer to cessation of production of tear or saliva production respectively.
  • May be primary autoimmune or part of another autoimmune condition.
  • Causes of xerostomia:
    • Dysautonomia
    • Infectious sialadenitis
    • Neoplasia
    • Salivary amyloidosis
    • Head and neck radiation
    • Drugs
    • AutoI disease.

Tagging-PG