Difference between revisions of "Transgenic Animals - Anatomy & Physiology"
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* Many mouse transgenics have been created to serve as models for human genetic diseases. | * Many mouse transgenics have been created to serve as models for human genetic diseases. | ||
* Less successful in other species, but goats have been created that secrete human [[Haemostasis - Pathology#Factor VIII|factor VIII]] in their milk. | * Less successful in other species, but goats have been created that secrete human [[Haemostasis - Pathology#Factor VIII|factor VIII]] in their milk. | ||
| − | ** Cheap treatment for [[ | + | ** Cheap treatment for [[Coagulation Factor Deficiency|bleeding disorders]] with little risk of disease transfer. |
* Area of much future development. | * Area of much future development. | ||
* Injection of specific gene constructs into the newly fertilized [[The Ovary - Oocytes - Anatomy & Physiology|oocyte]], so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual. | * Injection of specific gene constructs into the newly fertilized [[The Ovary - Oocytes - Anatomy & Physiology|oocyte]], so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual. | ||
Revision as of 09:51, 29 September 2010
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- Many mouse transgenics have been created to serve as models for human genetic diseases.
- Less successful in other species, but goats have been created that secrete human factor VIII in their milk.
- Cheap treatment for bleeding disorders with little risk of disease transfer.
- Area of much future development.
- Injection of specific gene constructs into the newly fertilized oocyte, so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual.
- Constructs may be from the same or different species as the oocyte.