**[[Macrocyclic Lactones|Ivermectin]] has greater efficacy against bots, but this has to be weighed against [[Macrocyclic Lactones|moxidectin]] which claims greater efficacy against [[Strongyles - Donkey#Small strongyles – Cyathostomins|encysted cyathostomes]] which are often more problematic at the time of year when treatment against bots would be given. | **[[Macrocyclic Lactones|Ivermectin]] has greater efficacy against bots, but this has to be weighed against [[Macrocyclic Lactones|moxidectin]] which claims greater efficacy against [[Strongyles - Donkey#Small strongyles – Cyathostomins|encysted cyathostomes]] which are often more problematic at the time of year when treatment against bots would be given. |