Difference between revisions of "Hypervitaminosis A"
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| + | bones | ||
[[Image:Hypervitaminosis A.jpg|right|thumb|100px|<small><center>Hypervitaminosis A (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]] | [[Image:Hypervitaminosis A.jpg|right|thumb|100px|<small><center>Hypervitaminosis A (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]] | ||
*Main lesions: | *Main lesions: | ||
**Injury to growth cartilage -> [[Bones - Anatomy & Physiology|premature closure of growth plate]] | **Injury to growth cartilage -> [[Bones - Anatomy & Physiology|premature closure of growth plate]] | ||
| − | **[[ | + | **[[Osteoporosis|Osteoporosis]] |
**'''Exostoses''' | **'''Exostoses''' | ||
**[[Musculoskeletal Terminology - Pathology|Osteophyte]] formation in prolonged exposure | **[[Musculoskeletal Terminology - Pathology|Osteophyte]] formation in prolonged exposure | ||
| Line 10: | Line 11: | ||
*Can also be teratogenic, especially in pigs ([[Cleft Palate|cleft plate]] and abortions) | *Can also be teratogenic, especially in pigs ([[Cleft Palate|cleft plate]] and abortions) | ||
| + | |||
| + | joints | ||
| + | *May cause spondylosis of cervical vertebrae | ||
| + | *Mainly on dorsolateral surface | ||
| + | *Also in elbow and shoulder joints -> fixation of joint | ||
| + | *May resolve with changes of diet | ||
| + | |||
| + | [[Category:Joints - Degenerative Pathology]] | ||
[[Category:Bones - Metabolic Pathology]] | [[Category:Bones - Metabolic Pathology]] | ||
[[Category:Toxicology]] | [[Category:Toxicology]] | ||
Latest revision as of 15:40, 3 March 2011
bones
- Main lesions:
- Injury to growth cartilage -> premature closure of growth plate
- Osteoporosis
- Exostoses
- Osteophyte formation in prolonged exposure
- In cats fed bovine liver for prolonged periods
- Rich in vitamin A in grazing animals
- Vertebrae fuse with each other due to bone proliferation - cervical spondylosis (ankylosing exostosis of the vertebral column), especially in the neck
- Can also be teratogenic, especially in pigs (cleft plate and abortions)
joints
- May cause spondylosis of cervical vertebrae
- Mainly on dorsolateral surface
- Also in elbow and shoulder joints -> fixation of joint
- May resolve with changes of diet