Difference between revisions of "Equine Rhabdomyolysis"

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(Created page with "*'''Azoturia''' (Monday morning disease) **Acute **Due to exercise following a prolonged period of rest **Clincal signs: ***Unable to move ***Sweating ***Tremors ***Swollen and h...")
 
 
(One intermediate revision by the same user not shown)
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***Salmon pink muscles -> dark, moist, swollen +/- pale streaks
 
***Salmon pink muscles -> dark, moist, swollen +/- pale streaks
 
**Histologically:
 
**Histologically:
***Segmental myofibre [[Muscles Degenerative - Pathology#Necrosis|necrosis]]
+
***Segmental myofibre [[Muscle Necrosis|necrosis]]
 
****Multifocal and monophasic, but may be multiphasic if repeated bouts
 
****Multifocal and monophasic, but may be multiphasic if repeated bouts
 
***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
 
***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
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[[Category:Muscles - Degenerative Pathology]]
 
[[Category:Muscles - Degenerative Pathology]]
 +
[[Category:To Do - Major]]

Latest revision as of 15:59, 25 July 2011

  • Azoturia (Monday morning disease)
    • Acute
    • Due to exercise following a prolonged period of rest
    • Clincal signs:
      • Unable to move
      • Sweating
      • Tremors
      • Swollen and hard lumbar, gluteal and femoral muscles
    • Myoglobin leaks from muscle cells -> leaks into urine -> urine is dark red/brown (myoglobinuria) -> damages renal tubules
    • Grossly:
      • Salmon pink muscles -> dark, moist, swollen +/- pale streaks
    • Histologically:
      • Segmental myofibre necrosis
        • Multifocal and monophasic, but may be multiphasic if repeated bouts
      • Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
      • Minor inflammatory reaction and calcification
  • Tying-up
    • Similar to azoturia but much milder
    • Grossly - normal muscle
    • Histologically - same as azoturia