Difference between revisions of "Granulomatous Meningoencephalitis"
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(Created page with "(GME) * An idiopathic CNS conditon * May occur as: ** A disseminated disease ** A focal mass lesion ** A primary occular disease * Brain...") |
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(GME) | (GME) | ||
| − | * An | + | * An idiopathic CNS conditon |
* May occur as: | * May occur as: | ||
** A disseminated disease | ** A disseminated disease | ||
| Line 25: | Line 25: | ||
| − | [[:Category:CNS Non-Infectious Inflammatory Diseases]] | + | * A non-infectious central nervous inflammatory disease |
| + | * May occur as: | ||
| + | ** A disseminated disease | ||
| + | ** A focal mass lesion | ||
| + | ** A primary occular disease | ||
| + | * Brainstem signs are common, although the forebrain is primarily affected. | ||
| + | * May be incorrectly diagnosed as lymphoma. | ||
| + | * Changes are apparent in the CSF. | ||
| + | ** There is usually a mononucloear pleocytosis. | ||
| + | ** Sometimes only protein is elveated. | ||
| + | * Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging. | ||
| + | ** However, biopsy is required for a definative diagnosis. | ||
| + | * Life span is between 6 months and 1 year from diagnosis. | ||
| + | |||
| + | |||
| + | [[Category:Central Nervous System - Idiopathic Pathology]] | ||
| + | [[Category:CNS Non-Infectious Inflammatory Diseases]] | ||
Latest revision as of 13:20, 13 February 2019
(GME)
- An idiopathic CNS conditon
- May occur as:
- A disseminated disease
- A focal mass lesion
- A primary occular disease
- Brainstem signs are common, although the forebrain is primarily affected.
- May be incorrectly diagnosed as lymphoma.
- Changes are apparent in the CSF.
- There is usually a mononucloear pleocytosis.
- Sometimes only protein is elveated.
- Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.
- However, biopsy is required for a definative diagnosis.
- Life span is between 6 months and 1 year from diagnosis.
Treatment
- Immunosuppression:
- Corticosteroids
- Azathioprine
- Cycophosphamide
- Surgery
- This is only appropriate if there is a focal mass.
- Radiation therapy.
- A non-infectious central nervous inflammatory disease
- May occur as:
- A disseminated disease
- A focal mass lesion
- A primary occular disease
- Brainstem signs are common, although the forebrain is primarily affected.
- May be incorrectly diagnosed as lymphoma.
- Changes are apparent in the CSF.
- There is usually a mononucloear pleocytosis.
- Sometimes only protein is elveated.
- Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.
- However, biopsy is required for a definative diagnosis.
- Life span is between 6 months and 1 year from diagnosis.