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| − | {{review}} | + | {{frontpage |
| | + | |pagetitle =Pseudomonas and Burkholderia species |
| | + | |pagebody = ''Pseudomonas'' and ''Burkholderia'' species are gram-negative rods that are found in the soil and water worldwide. Both species cause opportunistic infections. |
| | + | |contenttitle =Content |
| | + | |contentbody =<big><b> |
| | + | <categorytree mode=pages>Pseudomonas and Burkholderia species</categorytree> |
| | + | </b></big> |
| | + | |logo =bugs-logo copy.png |
| | + | }} |
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| − | ===Overview===
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| − | *Organisms found in soil and water worldwide
| + | [[Category:Bacterial Organisms]] |
| − | *''Burkholderia mallei'' causes [[Respiratory Bacterial Infections - Pathology#Glanders|glanders]]; rodents act as reservoir of infection
| + | [[Category:Gram_negative_bacteria]] |
| − | *''Burkholderia pseudomallei'' causes meliodosis
| + | [[Category:Rods]] |
| − | *''Pseudomonas aeruginosa'', found on skin, mucous membranes and in faeces, causes opportunistic infections
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| − | | |
| − | ===Characteristics===
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| − | *Gram-negative rods
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| − | *Obligate aerobes
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| − | *Oxidase and catalase positive
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| − | *''Pseudomonas'' species and ''Burkholderia pseudomallei'' motile by polar flagellae
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| − | *''Burkholderia mallei'' non-motile
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| − | ===''[[Pseudomonas aeruginosa]]''===
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| − | ===''[[Burkholderia mallei]]''===
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| − | ===''Burkholderia pseudomallei===
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| − | *Causes [[Respiratory Bacterial Infections - Pathology#Melioidosis (Pseudoglanders)|melioidosis]] - endemic in Asia and Australia
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| − | *Primarily infects rodents
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| − | *Pathogenesis:
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| − | **Infection via ingestion, inhalation or skin wounds from environment
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| − | **Exotoxin, dermonecrotic protease and lecithinase implicated in pathogenicity
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| − | **Strain virulence and host immunosuppression important
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| − | *Clinical infections:
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| − | **Opportunistic infection with stress and immunosuppression predisposing to disease
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| − | **Abscesses develop in many organs including lungs, spleen, liver, joints, CNS, upper respiratory tract
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| − | **Chronic, debilitating, progressive disease with long incubation period
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| − | **Many animal species susceptible
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| − | **Referred to as pseudoglanders in horses
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| − | *Diagnosis:
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| − | **Specimens: pus from abscesses, affected tissues, blood
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| − | **Fluorescent antibody technique on tissue smears
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| − | **Blood agar and MacConkey agar plates, incubated aerobically
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| − | **Colonies have musty smell
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| − | **Lactose fermentation on MacConkey
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| − | **Slide agglutination
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| − | **ELISA, complement fixation and indirect haemagglutination tests for serum antibodies
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| − | *Treatment/control: slaughter of infected animals where exotic
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| − | [[Category:Bacteria]][[Category:Gram_negative_bacteria]][[Category:Rods]]
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