Difference between revisions of "Category:Asfarviridae"
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| − | Asfarviridae | + | |pagetitle =Asfarviridae |
| + | |pagebody = Asfarviridae contains asfivirus, which is the virus of African Swine Fever. This is a serious exotic virus that should not be confused with [[Classical Swine Fever]]. | ||
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| − | =Morphology= | + | <categorytree mode=pages>Asfarviridae</categorytree> |
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| + | ==Morphology== | ||
*Large, enveloped, icosahedral, '''cytoplasmic''' DNA virus | *Large, enveloped, icosahedral, '''cytoplasmic''' DNA virus | ||
| − | =Virulence and Pathogenesis= | + | ==Virulence and Pathogenesis== |
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks''' | *Infects either '''upper respiratory tract''' or '''skin''' via '''ticks''' | ||
| − | *Enters bloodstream in [[Monocytes | + | *Enters bloodstream in [[Monocytes|monocytes]] |
*Reaches viscera and bone marrow within days | *Reaches viscera and bone marrow within days | ||
*Induces a '''clotting defect''' and '''hemolysis''' in red blood cells | *Induces a '''clotting defect''' and '''hemolysis''' in red blood cells | ||
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*General cell signal transduction is blocked, decreasing non-specific immunity | *General cell signal transduction is blocked, decreasing non-specific immunity | ||
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| − | + | [[Category:Viral Organisms]] | |
| − | + | [[Category:To_Do_-_Clinical/Viruses]] | |
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Latest revision as of 23:34, 15 June 2016
Asfarviridae
Asfarviridae contains asfivirus, which is the virus of African Swine Fever. This is a serious exotic virus that should not be confused with Classical Swine Fever.
Morphology
- Large, enveloped, icosahedral, cytoplasmic DNA virus
Virulence and Pathogenesis
- Infects either upper respiratory tract or skin via ticks
- Enters bloodstream in monocytes
- Reaches viscera and bone marrow within days
- Induces a clotting defect and hemolysis in red blood cells
- Also affects lymphocytes:
- Infects Th cells and causes them not to produce B-stimulating cytokines
- Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
- General cell signal transduction is blocked, decreasing non-specific immunity
Pages in category "Asfarviridae"
This category contains only the following page.