Difference between revisions of "Category:Enteritis, Villus Atrophy"

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(Created page with '==Villus Atrophy== * Commonly seen in enteric disease. * Occurs when more enterocytes are lost than are produced in the crypts. * Causes malabsorption of nutrients and water. …')
 
 
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==Villus Atrophy==
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{{frontpage
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|pagetitle =Enteritis, Villus Atrophy
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* Commonly seen in enteric disease.
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|pagebody = * Commonly seen in enteric disease.
 
* Occurs when more enterocytes are lost than are produced in the crypts.
 
* Occurs when more enterocytes are lost than are produced in the crypts.
 
* Causes  malabsorption of nutrients and water.
 
* Causes  malabsorption of nutrients and water.
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* There are two main types of villus atrophy:
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* There are two main types of villus atrophy, with and without damage to the crypts.
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|contenttitle =Content
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===Villus atrophy with intact/hypertrophic crypt glands===
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|contentbody =<big><b>
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* Insult affects the villus enterocytes leading to increased loss.
 
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** Under mild insult, villi may fully regenerate.
 
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** Severe insult leads to immature cells on the villus.
 
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*** Secrete water and electrolytes into lumen.
 
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* Examples include:
 
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** '''Rotavirus, Coronavirus'''
 
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*** Infect villus enterocytes.
 
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** '''Coccidia'''
 
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*** Infect surface enterocytes.
 
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** '''Nematodes'''
 
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*** Abrase surface.
 
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===Villus atrophy with damage to crypts===
 
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* The primary insult is to crypt cells.
 
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** Crypt cell death leads to dilated gland lumens (cysts).
 
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** Production is impaired, eventually leading to insufficient cells for villi. 
 
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* Enterocytes lost to lumen are replaced by increasingly immature cells.
 
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** Gives rise to severe malabsorption.
 
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* If damage is severe, erosions/ulcers may form which may eventually heal.  
 
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** Even if there are no ulcers, damage can be long-term
 
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*** Causes long-term malabsorption.
 
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* Examples include:
 
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** '''Parvovirus'''
 
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*** Target crypt cells.
 
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** '''Lymphoma'''
 
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*** Numerous neoplastic lymphocytes compress crypts.
 
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** '''Cytotoxic chemicals'''
 
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*** Dividing crypt cells are susceptible.
 
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==Enteritis Particularly Associated with Villus Atrophy==
 
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===[[Reoviridae#Rotaviruses|Rotavirus]]===
 
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===[[Cryptosporidium|Cryptosporidium]]===
 
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* Small coccidial parasite.
 
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* Affects calf, lamb, piglet, kitten.
 
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* Increasingly important as part of the neonatal [[Intestine Diarrhoea - Pathology|diarrhoea]] complex in calves.
 
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* Zoonosis.
 
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====Pathology====
 
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=====Gross=====
 
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* Intestines diffusely reddened, with fluid contents.
 
  
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=====Histological=====
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<categorytree mode=pages>Enteritis, Villus Atrophy</categorytree>
  
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* Tiny parasites on surface of epithelium.
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</b></big>
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* Villus atrophy and fusion.
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|logo =path-logo.png
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* Iinflammation (mainly lymphoid) in crypts and lamina propria.
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}}
  
 
[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]
 
[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]

Latest revision as of 18:32, 15 February 2011

Enteritis, Villus Atrophy

* Commonly seen in enteric disease.

  • Occurs when more enterocytes are lost than are produced in the crypts.
  • Causes malabsorption of nutrients and water.
  • There are two main types of villus atrophy, with and without damage to the crypts.

Content

▼ Enteritis, Villus Atrophy
  Cryptosporidium
  Enterocytes, Epithelial Renewal
  Rotaviruses
  Villus atrophy with damage to crypts
  Villus atrophy with intact/hypertrophic crypt glands

Pages in category "Enteritis, Villus Atrophy"

The following 5 pages are in this category, out of 5 total.

C

E

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