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| − | ==[[Liver, Hydropic Degeneration]]== | + | {{frontpage |
| | + | |pagetitle =Liver - Degenerative Pathology |
| | + | |pagebody = |
| | + | |contenttitle =Content |
| | + | |contentbody =<big><b> |
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| − | [[Hepatic Lipidosis]]
| + | <categorytree mode=pages>Liver - Degenerative Pathology</categorytree> |
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| | + | </b></big> |
| | + | |logo =path-logo.png |
| | + | }} |
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| − | ====[[Equine Hyperlipidemia]]====
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| − | ====Ovine White Liver Disease====
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| − | *Australia and Europe
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| − | *young lambs on lush pasture
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| − | *clinical signs
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| − | **ill thrift
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| − | **anorexia
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| − | **jaundice
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| − | **photosensitisation
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| − | *treatment
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| − | **responsive to Vitamin B12 and cobalt
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| − |
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| − | ===associated with derangement of carbohydrate metabolism===
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| − | ====[[DM|Diabetes mellitus]]====
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| − | *where there is insufficient insulin or a decrease in number of insulin receptors in cells
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| − | *seen mostly in dogs
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| − | *produces a markedly fatty [[Liver - Anatomy & Physiology|liver]] due to release of fat from the fat stores for use as an energy source
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| − | ====Ketosis====
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| − | *due to an excessive drain on carbohydrate stores because pregnant and lactating animals have a continuous demand for glucose
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| − | *ketosis results when fat metabolism which occurs in response to the increased energy demand is excessive
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| − | *ketone bodies accumulate in the blood and there is marked fatty change in the [[Liver - Anatomy & Physiology|liver]]
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| − | *can occur in starvation but commonly seen in two conditions in livestock:
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| − | =====ketosis of cattle (acetonemia)=====
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| − | *occurs in high yielding dairy cows a few weeks postpartum
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| − | *due to excessive loss of glucose in the milk
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| − | *milk yield drops
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| − | *smell of ketones on the breath
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| − | *ketones excreted in the milk
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| − | *self-limiting condition
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| − | =====pregnancy toxaemia in sheep=====
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| − | *occurs in ewes in late pregnancy carrying twin lambs ''''twin lamb disease''''
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| − | *drain of carbohydrate stores is due to rapidly growing foetuses
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| − | *serious condition and highly fatal
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| − | *clinical signs (neurological)
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| − | **apparent blindness
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| − | **dullness
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| − | **convulsions
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| − | **coma
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| − | *sequelae
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| − | **foetuses die
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| − | **apparent recovery in ewe until toxaemia from the decomposing foetuses results in the ewe's death
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| − |
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| − | ===associated with anoxia and toxaemia===
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| − | ====anoxia====
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| − | *passive congestion
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| − | *anaemias
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| − | ====toxaemia====
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| − | *toxins absorbed from the gut interfere with many stages of triglyceride metabolism
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| | [[Category:Liver_-_Pathology]] | | [[Category:Liver_-_Pathology]] |
