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| − | [[Pancreatitis, Acute Haemorrhagic]]
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| | + | |pagetitle =Pancreas - Inflammatory Pathology |
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| | + | <categorytree mode=pages>Pancreas - Inflammatory Pathology</categorytree> |
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| − | ==Chronic interstitial pancreatitis==
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| − | *Ongoing inflammation with progression to irreversible damage and impaired function
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| − | *Fibrosis and reduction in acinar mass
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| − | *Can happen in all species as a consequence of obstruction of the pancreatic ducts
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| − | *Vitamin A deficiency may predispose
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| − | *Most commonly in dog, but also in cat, horse and cattle
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| − | *The [[Pancreas - Anatomy & Physiology#Endocrine|islets of Langerhans]] tend to be preserved
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| − | *'''In dogs'''
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| − | **Repeated mild episodes of acute pancreatitis and pancreatic necrosis results in progressive destruction and pancreatic fibrosis and chronic pancreatitis
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| − | **If significant proportion of pancreas is affected, signs of [[EPI|EPI]] develop +/- [[DM|DM]]
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| − | **''Gross appearance''
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| − | ***[[Pancreas - Anatomy & Physiology|Pancreas]] is distorted, shrunken
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| − | ***Nodular mass with fibrous adhesions to adjacent tissue
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| − | ***May be an incidental finding on necropsy
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| − | **Focal pancreatitis may occur during [[Parvoviridae|canine parvovirus]] and [[Paramyxoviridae#Canine Distemper Virus (CDV)|distemper virus]] infection
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| − | *'''In cats'''
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| − | **[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=6937 Image of chronic pancreatitis and fibrosis in a cat from Cornell Veterinary Medicine]
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| − | **Chronic relapsing condition is more common than the acute condition in cats
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| − | **Fibrosis, ductular ectasia with cyst formation and inflammation
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| − | **Associated with hepatic lipidosis, cholangiohepatitis and inflammatory bowel disease.
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| − | *'''In sheep'''
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| − | **Necrosis of [[Pancreas - Anatomy & Physiology#Exocrine|exocrine pancreatic cells]] followed by fibrosis can be caused by zinc toxicosis
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| − | **Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
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| − | *'''In horses'''
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| − | **Occurs sporadically
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| − | **Usually as a consequence of [[Pancreas Parasitic - Pathology|parasitic migration]] or from ascending bacterial infection of pancreatic ducts
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| − | **Can occur alongside '''chronic eosinophilic gastroenteritis'''
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| − | **Usually clinically silent
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| − | **Organ tends to be replaced by scar tissue
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| − | *'''In cattle'''
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| − | **Focal pancreatitis may occur during [[picornaviridae#Foot and Mouth Disease Virus|Foot and Mouth disease]] resulting in [[DM|diabetes mellitus]] during recovery
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| | [[Category:Pancreas_-_Pathology]] | | [[Category:Pancreas_-_Pathology]] |
