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| <categorytree mode=pages>Lymph Nodes</categorytree> | | <categorytree mode=pages>Lymph Nodes</categorytree> |
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− | [[:Category:Lymph Node Responses in Disease]]
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− | ==Role of the [[Lymph Node in Inflammation]]==
| + | [[Category:Secondary Lymphoid Tissue|A]] |
− | ''Back to [[Inflammation - Pathology]]
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− | ==Diseases Involving [[Reactive Node Diseases]]==
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− | ==Diseases Parasitising the Lymphocytes==
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− | *organism grows in the lymphocytes and ruptures them
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− | *if large infecting dose
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− | :- may be rapidly fatal since animal may no tb e able to mount an immunological attack | |
− | *if smaller infecting dose
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− | :- loss of mature lymphocytes causes a dramatic stimulation of the remaining lymphocyte precursors
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− | :- node hyperplasia follows
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− | :- competition between lymphocytolysis by the organism and lymphocyte production by the nodes
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− | :- clinically
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− | ::- may be swelling of the node at one stage and reduction in size at another
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− | ===canine distemper===
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− | *virus
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− | ===swine fever===
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− | *virus
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− | ===bovine east coast fever===
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− | *protozoan
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− | ===[[Leishmania|Leishmaniasis in the dog]]===
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− | ==Other Lymphadenopathy==
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− | ===Lymph node pigmentation===
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− | *Lungs
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− | :- anthracosis
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− | ::- carbon derived from soot finds its way to the local nodes in macrophages
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− | *Skin
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− | :- dermatopathic lymphadenopathy or melanic reticulosis
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− | ::- in pigmented animals, especially black dogs
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− | ::- chronic inflammatory skin conditions lead to melanin deposition in hyperplastic nodules
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− | :- also occurs in nodes draining skin melanomas where the pigment may be the result of skin ulceration or secondary tumour deposit
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− | ::- these two should not be confused since the prognosis is very different following surgery
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− | ===Emphysema===
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− | *interstitial emphysema
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− | :- common in cases of dyspnoea
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− | :- more commonly affects bovine lung
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− | ::- due to well developed pulmonary lobulation and hence much loose interstitial lung tissue
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− | *collection of gas bubbles in bronchial and mediastinal lymph nodes
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− | :- gas travels to these nodes after gaining entry to the many lymphatic vessels present in the interstitial tissue
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− | ===Neoplasia===
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− | * Primary tumours
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− | ** Lymphosarcoma (lymphoma)
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− | :- of lymphoid cells with lymph node enlargement
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− | :- smooth, pale hemogenous but may have areas of necrosis
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− | :- may cause [[Parathyroid Glands - Pathology#Pseudo-Hyperparathyroidism|pseudo-hyperparathyroidism]]
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− | * Secondary tumours
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− | :- nodes often involved in the spread of tumours by extension or metastasis
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− | :- usually carcinomas
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− | ==Haemal Lymph Nodes==
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− | *ruminants only
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− | *small; dark red/brown
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− | *develop during foetal life
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− | :- lymph node primordia which lose their lymph vessles
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− | :- receive all cells and antigen from the BLOOD
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− | *functional significance unclear
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− | *probably respond to blood-borne antigen
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− | [[Category:Inflammation]]
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