Difference between revisions of "Phosphorus"

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Hyperphosphataemia occurs from excessive dietary phosphorus, hypervitaminosis D and renal disease. Phosphorus may be the only biochemical parameter increased in renal failure. Hypophosphataemia may occur with anorexia, starvation or other nutritional imbalances. A calcium:phosphorus ratio of less than 1:1 is suggestive of renal disease.
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==Overview==
  
[[Category:Lizard_and_Snake_Glossary]]
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Phosphorus is the third most abundant intracellular ion:
[[Phosphorus - Reptiles]]
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1. Potassium
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2. Magnesium
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3. Phosphorus (as Phosphate)
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Within the body it is found as Phosphate ions, or Phosphate within bone. The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.
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==Homeostasis==
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Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via ''passive diffusion'' and ''[[Calcium#Calcitriol (Active Vitamin D3)|vitamin D]] mediated active transport''. Phosphorus is excreted in the urine or saliva (particularly in ruminants).
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===Hormonal Regulation===
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[[Calcium#Parathyroid Hormone (PTH)|'''PTH''']]
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PTH mobilises phosphorus from bone, acting to increase the plasma concentration of P. It increases phosphorus loss in the urine and saliva, so ultimately, PTH acts to remove phosphorus from the body entirely.
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[[Calcium#Calcitriol (Active Vitamin D3)|'''Calcitriol''']]
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Calcitriol increases phosphorus absorption from the intestines.
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==Pathology==
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Diseases relating to phosphorus homeostasis include:
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1. [[Hyperparathyroidism |Primary and Secondary Hyperparathyroidism]]
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2. Hyperphosphataemia
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3. Hypophosphatemia
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{{Template:Learning
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|flashcards = [[Phosphorus_Homeostasis_Flash_Cards_- Anatomy & Physiology|Phosphorus homeostasis]].
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}}
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{{OpenPages}}
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[[Category:Endocrine System - Anatomy & Physiology]]
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[[Category:Electrolytes]]
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[[Category:A&P Done]]
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[[Category:Minerals]]

Latest revision as of 16:22, 12 April 2022


Overview

Phosphorus is the third most abundant intracellular ion:

1. Potassium

2. Magnesium

3. Phosphorus (as Phosphate)

Within the body it is found as Phosphate ions, or Phosphate within bone. The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.

Homeostasis

Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via passive diffusion and vitamin D mediated active transport. Phosphorus is excreted in the urine or saliva (particularly in ruminants).

Hormonal Regulation

PTH

PTH mobilises phosphorus from bone, acting to increase the plasma concentration of P. It increases phosphorus loss in the urine and saliva, so ultimately, PTH acts to remove phosphorus from the body entirely.

Calcitriol

Calcitriol increases phosphorus absorption from the intestines.

Pathology

Diseases relating to phosphorus homeostasis include:

1. Primary and Secondary Hyperparathyroidism

2. Hyperphosphataemia

3. Hypophosphatemia



Phosphorus Learning Resources
FlashcardsFlashcards logo.png
Flashcards
Test your knowledge using flashcard type questions
Phosphorus homeostasis.



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