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Neoplasia of the bladder is most commmon in dogs, cats and cattle.
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===Benign tumours===
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===Leiomyoma===
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*Occur in the smooth muscle of the bladder wall.
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*May be single or multiple, well defined white nodular projections.
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*If situated at the neck of the bladder, they can disrupt urinary flow.
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===Papilloma===
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*Bladder papillomas are uncommon.
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*Will often recur following excision.
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*Can lead to carcinomas.
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===Botryoid rhabdomyosarcoma===
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*Occurs in the bladder and less commonly the urethra of large breed dogs less than 18 months of age.
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*Embryonic myoblasts may be the origin. 
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*Appears as a large fungating mass, usually at the trigone of the bladder.
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*Highly infiltrative and metastatic.
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===[[LUT Vascular - Pathology#Haemorrhages|Bovine enzootic haematuria]]===
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==Malignant tumours==
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===Transitional cell carcinoma===
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*Most relevant in dogs and cats.
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*Spreads along and through the bladder wall.
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*Destroys the epithelium and invades the muscle layers.
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*Metastasis to regional nodes and the lungs occurs in approximately 50% of cases. 
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**Can also spread to the peritoneum or in a retrograde manner to the soft tissue and bone of the hindlimbs.
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===[[LUT Vascular - Pathology#Haemorrhages|Bovine enzootic haematuria]]===