| Line 47: |
Line 47: |
| | [[Rickettsia rickettsii]] | | [[Rickettsia rickettsii]] |
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| | + | [[Ehrlichia canis]] |
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| − | ===Canine monocytic ehrlichiosis===
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| − | *Generalised disease of dogs in tropical and subtropical regions
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| − | *Caused by ''Ehrlichia canis''
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| − | *The brown tick, ''Rhipicephalus sanguineus'', is the main vector
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| − | *Dogs may carry the organism for 2 years after resolution of clinical signs
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| − | *Clinical signs
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| − | **Incubation period of 3 weeks
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| − | **Acute, subclinical or chronic phases
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| − | **Acute phase: fever, thrombocytopenia, leukopenia and anaemia
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| − | **Subclinical phase: low blood cell numbers but minimal clinical signs; can progress to a severe disease, tropical canine pancytopenia
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| − | **Chronic phase: bone marrow depression, haemorrhages, neurological disease, peripheral oedema, emaciation and hypotensive shock
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| − | *Diagnosis
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| − | **''E. canis'' morulae present in mononuclear cells in Giemsa-stained blood smears
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| − | **Rising antibody titre detected by indirect immunofluorescence
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| − | **Culture in canine macrophages
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| − | *Treatment and control
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| − | **Doxycycline for 10 days
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| − | **Fluid therapy or blood transfusion
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| − | **Prophylactic tetracyclines
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