Difference between revisions of "Muscles Developmental - Pathology"
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Revision as of 17:31, 3 March 2011
Myofibrillar Hypoplasia
=Muscle Fibre Hyperplasia
Muscular Dystrophy
Glycogen Storage Disease
Steatosis
Myasthenia gravis (MG)
- Acquired
- Autoimmune disease
- Antibodies directed against acetyl choline receptors
- Associated with thymomas, megaoesophagus and dysphagia
- In adult dogs
- Autoimmune disease
- Congenital
- Inherited deficiency in acetyl choline receptors
- Rare
- Newfoundland, Jack Russel Terrier, Springer Spaniels – genetic predisposition
- In dogs – 4 DLA genes recognized: DLA-12, DLA-88, DLA-79 and DLA-64
- Associated with HLA gene in humans
- No antibodies against acetyl choline receptors in serum
- Non-specific muscle disuse atrophy and fibrosis or no changes on histology
- Both forms manifest as weakness which worsens on exercise