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Extensive evaluation of the renal disease and '''clinical evaluation of the patient''' should be completed prior to biopsy.
Extensive evaluation of the renal disease and '''clinical evaluation of the patient''' should be completed prior to biopsy.
A '''coagulation profile''' is essential prior to biopsy due to the considerable risk of haemorrhage.
A [[Coagulation Tests|'''coagulation profile''']] is essential prior to biopsy due to the considerable risk of haemorrhage.
==Needle Biopsy==
==Needle Biopsy==
The cortex is usually sampled '''several times'''.
The cortex is usually sampled '''several times'''.
For animals with glomerular disease, one sample should be placed in formalin for light microscopy, one sample placed in a fixative, and one sample frozen for immunofluorescence microscopy.
For animals with glomerular disease, one sample should be placed in formalin for light microscopy, one sample placed in a fixative, and one sample frozen for [[immunofluorescence]] microscopy.
==Wedge biopsy==
==Wedge Biopsy==
A wedge biopsy obtained at surgery provides '''superior quality samples'''.
A wedge biopsy obtained at surgery provides '''superior quality samples'''.
Digital pressure can be applied for 5 to 10 minutes if bleeding occurs, or the omentum can be sutured over the area with interrupted sutures.
Digital pressure can be applied for 5 to 10 minutes if bleeding occurs, or the omentum can be sutured over the area with interrupted sutures.
==Post-procedure considerations==
==Post-procedure Considerations==
After renal biopsy, patients should be '''diuresed for several hours''' to decrease the risk of blood clot formation and obstruction of the renal pelvis or urethra.
After renal biopsy, patients should be '''diuresed for several hours''' to decrease the risk of blood clot formation and obstruction of the renal pelvis or urethra.
Tobias, K. (2009) '''Manual of small animal soft tissue surgery''' ''John Wiley and Sons''
Tobias, K. (2009) '''Manual of small animal soft tissue surgery''' ''John Wiley and Sons''
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[[Category:Clinical Techniques]]
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