Anus - Anatomy & Physiology

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Structure

Histology

• At the anus, the columnar intestinal epithelium is replaced by the stratified squamous epithelium of the skin.
• As the muscosa changes from columnar to cutaneous, three zones are created:
  • Columnar
    • Has many longitudinal folds.
    • Divided from the rectum by the anorectal line.
      • This is a line where the mucosa is stratified squamous epithelium containing lots of lymphoid tissue.
  • Intermediate
    • Divided from the cutaneous zone by the anocutaneous line.
  • Cutaneous
    • Skin.
    • Stratified squamous epithelium.
    • Surrounds the anus.
    • Excretory ducts of the anal sacs open into this region.
      • Anal sacs are large, coiled apocrine tubules.
      • Anal sacs have many glands in their walls.
      • These glands are tubuloalveolar and produce a fatty secretion.
      • Anal sacs are clinically important as they are commonly diseased in dogs - frequently, they become enlarged due to accumulated secretion.