Difference between revisions of "Category:Asfarviridae"

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=Introduction=
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{{frontpage
Asfarviridae receives it's name from [[African Swine Fever|'''A'''frican '''S'''wine '''F'''ever virus]], which is derived from any of this family of viruses.  ASF is a serious exotic virus that should not be confused with [[Classical Swine Fever]].
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|pagetitle =Asfarviridae
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|pagebody = Asfarviridae receives it's name from [[African Swine Fever|'''A'''frican '''S'''wine '''F'''ever virus]], which is derived from any of this family of viruses.  ASF is a serious exotic virus that should not be confused with [[Classical Swine Fever]].
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=Morphology=
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<categorytree mode=pages>Asfarviridae</categorytree>
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==Morphology==
 
*Large, enveloped, icosahedral, '''cytoplasmic''' DNA virus
 
*Large, enveloped, icosahedral, '''cytoplasmic''' DNA virus
  
=Virulence and Pathogenesis=
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==Virulence and Pathogenesis==
 
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks'''
 
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks'''
 
*Enters bloodstream in [[Monocytes - WikiBlood|monocytes]]
 
*Enters bloodstream in [[Monocytes - WikiBlood|monocytes]]

Revision as of 12:31, 23 May 2010

Asfarviridae

Asfarviridae receives it's name from African Swine Fever virus, which is derived from any of this family of viruses. ASF is a serious exotic virus that should not be confused with Classical Swine Fever.


Morphology

  • Large, enveloped, icosahedral, cytoplasmic DNA virus

Virulence and Pathogenesis

  • Infects either upper respiratory tract or skin via ticks
  • Enters bloodstream in monocytes
  • Reaches viscera and bone marrow within days
  • Induces a clotting defect and hemolysis in red blood cells
  • Also affects lymphocytes:
    • Infects Th cells and causes them not to produce B-stimulating cytokines
    • Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
  • General cell signal transduction is blocked, decreasing non-specific immunity

Pages in category "Asfarviridae"

This category contains only the following page.