6,273
edits
Changes
Ferrets (Laboratory) - Pathology (view source)
Revision as of 15:42, 4 March 2011
, 15:42, 4 March 2011→Reproductive System
<br />
<br />
Gross lesions will include a prominently swollen vulva. Associated signs of hyperoestrogenism will include pale mucus membranes, alopecia, thin watery blood, haemorrhages throughout the body, pyometra, bronchopneumonia and vaginitis. Microscopic lesions will include aplastic anemia (PCV <20%). Characteristic lesions will include hypocellularity of the bone marrow and some evidence of haemorrhage in lymph nodes and spleen. Supparative metritis or pneumonia may also be seen as a result of the leukopenia.
Gross lesions will include a prominently swollen vulva. Associated signs of hyperoestrogenism will include pale mucus membranes, alopecia, thin watery blood, haemorrhages throughout the body, pyometra, bronchopneumonia and vaginitis. Microscopic lesions will include aplastic anemia (PCV <20%). Characteristic lesions will include hypocellularity of the bone marrow and some evidence of haemorrhage in lymph nodes and spleen. Supparative metritis or pneumonia may also be seen as a result of the leukopenia.
<br />
<br />
'''Mastitis'''
<br />
Mastitis is occasionally seen in pregnant jills during the first few weeks of lactation with haemolytic ''E. coli'' being the most commonly isolated causative organism. This usually results in gangrenous mastitis and if untreated jills can become septic and/or endotoxemic. ''Staphylococcus aureus'' has also been suggested as another potential causative agent, although this infection produces more of a supparative and less necrotic form of mastitis.
<br />
<br />
Gross lesions will include swelling in any affected teats that may also appear necrotic, black, firm and non-painful. If this causative agent is ''Staphylococcus aureus'', the mammary glands will be hot, painful, reddish and purulent exudate may be expressed from the lactiferous ducts. Microscopic lesions associated with ''E. coli'' will include diffuse severe coagulative necrosis that often extends into the adjacent adipose tissue and muscle. There will be large pockets of haemorrhage and oedema together with numerous bacteria. Areas of infarction will be demarcated with a line of degenerate neutrophils and cellular debris. Vascular thrombosis may also be seen. Other microscopic signs of sepsis/endotoxaemia may be seen including margination of neutrophils in the pulmonary capillaries and hypertrophy of Kupfer cells with hepatic sinusoids. Microscopic lesions regarding ''Staphylococcus aureus'' infections may include less evidence of infarction, although a purulent galactophoritis and mastitis will be present along with numerous bacteria.
<br />
<br />
<br />
<br />