Difference between revisions of "Morantel"

From WikiVet English
Jump to navigation Jump to search
Line 8: Line 8:
 
}}
 
}}
  
These belong to the tetrahydropyrimidines class of drugs and a known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
+
It belongs to the tetrahydropyrimidines class of drugs which are known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
  
 
==Levamisole==
 
* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
 
* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
 
* It is a cholinergic agonist at neural and neuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
 
* It is rapidly absorbed and excreted and its potency is related to its peak plasma concentrations. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.
 
 
==Morantel==
 
 
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 
* It has limited activity against larval forms and so has little uses.
 
* It has limited activity against larval forms and so has little uses.
 
* Morantel is used in some rumenal boluses.
 
* Morantel is used in some rumenal boluses.
 
* Pyrantel, a similar product, is used for against equine [[cestodes]].
 
* Pyrantel, a similar product, is used for against equine [[cestodes]].

Revision as of 21:31, 29 September 2009


WikiDrugsWikiDrugs Banner.png
WIKIDRUGS
ANTHELMINTIC DRUGS


It belongs to the tetrahydropyrimidines class of drugs which are known by farmers as yellow drenches. The product code in the UK is 2-LM.

  • This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
  • It has limited activity against larval forms and so has little uses.
  • Morantel is used in some rumenal boluses.
  • Pyrantel, a similar product, is used for against equine cestodes.