|
|
| Line 26: |
Line 26: |
| | [[Histoplasmosis]] | | [[Histoplasmosis]] |
| | | | |
| − | ==Zygomycosis==
| + | [[Zygomycosis]] |
| − | {| align="right"
| |
| − | |<gallery>Image:Mucor liver.jpg|<center><p>'''Mucor liver'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
| |
| − | |}
| |
| − | | |
| − | *Also known as mucormycosis, hyphomycosis and phycomycosis
| |
| − | | |
| − | *Caused by strains of ''Mucor, Absidia, Rhizopus'' and ''Mortierella''
| |
| − | **''Mucor circinelloides''(rare), ''Rhizomucor pusillus'' and ''R. meihi''
| |
| − | **''Absidia corymbifera'' often causes zygomycosis in cattle and pigs
| |
| − | **''Rhizopus arrhizus, R. microsporus'' and ''R. rhizopodormis''
| |
| − | **''Mortierella wolfi'' implicated in bovine abortion (mycotic placentitis), ''M. hygrophila'' in fowl and ''M.polycephala'' in cattle
| |
| − | | |
| − | *Occurs widely in nature
| |
| − | | |
| − | *Infection is by inhalation and ingestion
| |
| − | | |
| − | *Infects [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] of the [[Cardiorespiratory System - Anatomy & Physiology|respiratory]] and [[Alimentary - Anatomy & Physiology|alimentary tract]]
| |
| − | **[[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] enlarge and become caseous
| |
| − | **Can cause [[Alimentary - Anatomy & Physiology#Stomach|stomach]] and [[Small Intestine - Anatomy & Physiology|intestinal]] ulcers
| |
| − | | |
| − | | |
| − | *Granulomatous lesions which can ulcerate
| |
| − | {| align="right"
| |
| − | |<gallery>Image:Mucor rumen.jpg|<center><p>'''Mucor mould on the ruminal surface'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup?</center></gallery>
| |
| − | |}
| |
| − | *Mostly localised lesions but can be generalised
| |
| − | *Pigs
| |
| − | **Mediastinal and submandibular [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] lesions
| |
| − | **Embolic tumours in the [[Liver - Anatomy & Physiology|liver]] and [[Lungs - Anatomy & Physiology|lungs]]
| |
| − | **Can also be present in gastric ulcers
| |
| − | | |
| − | *Cattle
| |
| − | **Bronchial, mesenteric and mediastinal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] lesions
| |
| − | **Ulcers of the [[Nasal cavity - Anatomy & Physiology|nasal cavity]] and [[The Abomasum - Anatomy & Physiology|abomasum]] also occur
| |
| − | **Often contaminate the [[Gestation -Placenta - Anatomy & Physiology|placenta]]
| |
| − | | |
| − | *Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected
| |
| − | | |
| − | *Microscopically:
| |
| − | **Fragments of non-septate hyphae which are branched and coarse
| |
| − | **''Rhizomucor'' produce a thick, grey mycelium and have short, black, spherical sporangia
| |
| − | **''Mucor'' produce thick, colourless mycelium with no rhizoids. Globose spoangia with small spores are present and sporagiospores are simple or branched.
| |
| − | **''Absidia'' resemble ''Rhizopus'' grossly
| |
| − | **''Mortierella'' produce white, velvet colonies on Sabouraud's Dextrose and Blood agar
| |
| − | | |
| − | *Grows on Sabauraud's Dextrose agar
| |
| − | **Common contaminants
| |
| − | | |
| − | *Treatment is with [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]]
| |
| − | **Surgery is also an option in treatment
| |
| − | {| align="center"
| |
| − | |<gallery>Image:Saprolegnia salmon.jpg|<center><p>'''Saprolegnia salmon'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center>
| |
| − | Image:Saprolegnia.jpg|<center><p>'''Saprolegnia'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center>
| |
| − | Image:Sporangiospores.jpg|<center><p>'''Sporangiospores'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery>
| |
| − | |}
| |
| | | | |
| | ==Further Links== | | ==Further Links== |
| | | | |
| | *[[Antifungal Drugs]] | | *[[Antifungal Drugs]] |
