Difference between revisions of "Arcanobacter pyogenes"

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*[[Respiratory Bacterial Infections - Pathology#Acute exudative pneumonia|Acute exudative pneumonia]] and contributes to [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
 
*[[Respiratory Bacterial Infections - Pathology#Acute exudative pneumonia|Acute exudative pneumonia]] and contributes to [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
 
*May cause [[Muscles Inflammatory - Pathology#Abscesses|myositis]]
 
*May cause [[Muscles Inflammatory - Pathology#Abscesses|myositis]]
*Unclassified ''Actinomyces'' species isolated from closed cases of [[Bursae and Tendons Inflammatory - Pathology#Poll Evil and Fistulous Withers|Poll Evil and Fistulous Withers]]
 
 
  
 
===Treatment===
 
===Treatment===

Revision as of 20:39, 10 May 2010


Characteristics

  • Formerly known as Actinomyces pyogenes and Corynebacterium pyogenes
  • Small facultatively anaerobic rod
  • Grows slowly on blood agar to produce small, white colonies surrounded by a zone of beta-haemolysis after 48 hours
  • Produces hazy haemolysis after 24 hours; pin-point colonies after 48 hours
  • Coryneform morphology, like Chinese characters; may be curved with slightly swollen ends
  • Found in nasopharyngeal mucosa and genital tract of cattle, sheep, pigs


Pathogenicity

  • Opportunistic infections following injury or viral/mycoplasma infection in ruminants and pigs
  • Extracellular toxins including haemolysin, proteases, DNase and neurominidase
  • Haemolytic toxin, pyolysin, member of the thiol-activated cytolysins (pore-forming toxins); possibly cytotoxic to phagocytic cells; dermonecrotising activity


Clinical infections

Treatment

  • Penicillin or broad spectrum antibiotics