Difference between revisions of "Category:Brachyspira and Serpulina"

Revision as of 22:42, 14 May 2010

Anaerobic, intestinal spirochaetes, found in normal and diseased pigs
Enterophogens of pigs
B. hyodysenteriae, B. pilosicoli, B. innocens, Serpulina intermedia and S. murdochii occur in pigs
Carrier pigs shed B. hyodysenteriae for up to 3 months, acting as a source of infection for healthy pigs
Demonstrated in stained faecal smears or silver-stained histopathology sections
Cultured anaerobically on selective blood agar
Spirochaetes differentiated by pattern of haemolysis on blood agar as well as molecular techniques

Pathogenesis
- Motility in mucous allows colonisation of pig intestine
- Haemolytic and cytotoxic activiity important for virulence
- Attachment of B. pilosicoli to epithelial cells of colonic mucosa disrupts their function and leads to their shedding and oedema

The following 2 pages are in this category, out of 2 total.

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 [[Brachyspira pilosicoli]]
-**''B. pilosicoli'' causes porcine intestinal spirochaetosis
-**Infection is acquired via contaminated faeces
-**Disease spreads slowly through the herd
-**Dogs, rats, mice and flies may act as transport hosts
-*Clinical signs
-**''B. pilosicoli'' causes less severe signs than [[Brachyspira hyodysenteriae|swine dysentry]]; reduced feed conversion rates occur
-*Diagnosis
-**History, clinical signs and gross pathology
-**Anaerobic culture on blood agar with added antibiotics for at least 3 days
-**Immunofluorescence, DNA probes and biochemical tests
-**Serology using ELISA can be used on a herd basis
-**PCR
 [[Category:Spirochaetaceae]][[Category:Pig]]