Difference between revisions of "Bovine Papular Stomatitis"

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*Parapox virus
 
*Parapox virus
 
*Very similar disease to orf but seen in cattle and generally milder condition.   
 
*Very similar disease to orf but seen in cattle and generally milder condition.   
*'''Must be differentiated from [[#Foot and Mouth disease|Foot and Mouth Disease]] and [[#Bovine Viral Diarrhoea / Mucosal disease|Mucosal Disease.]]'''
+
*'''Must be differentiated from [[Foot and Mouth Disease]] and [[Bovine Viral Diarrhoea|Mucosal Disease.]]'''
 
*Sporadic, in cattle, less than 1 year old.  
 
*Sporadic, in cattle, less than 1 year old.  
 
*Develop papules on the muzzle, external nares and in the [[Oral Cavity Overview - Anatomy & Physiology|oral cavity]]; the [[Oesophagus - Anatomy & Physiology|oesophagus]] and [[Stomach and Abomasum - Anatomy & Physiology|forestomachs]] may also be affected.   
 
*Develop papules on the muzzle, external nares and in the [[Oral Cavity Overview - Anatomy & Physiology|oral cavity]]; the [[Oesophagus - Anatomy & Physiology|oesophagus]] and [[Stomach and Abomasum - Anatomy & Physiology|forestomachs]] may also be affected.   

Revision as of 15:42, 25 May 2010

Papular proliferative pathology

Ring Zone Lesions of BPS - Calf (Courtesy of Alun Williams (RVC))
  • Parapox virus
  • Very similar disease to orf but seen in cattle and generally milder condition.
  • Must be differentiated from Foot and Mouth Disease and Mucosal Disease.
  • Sporadic, in cattle, less than 1 year old.
  • Develop papules on the muzzle, external nares and in the oral cavity; the oesophagus and forestomachs may also be affected.
  • Usually heals spontaneously.
Pathogenesis
  • The early lesions are round areas of intense congestion up to 1.5 cm in diameter.
  • The centre becomes necrotic and slightly depressed.
  • Slow peripheral extension of this lesion gives a classical ring zone formation with concentric rings of
    • yellow (necrosis),
    • grey (epithelial hyperplasia)
    • red (congestion).
Histology
  • There are focal areas of hydropic degeneration in the stratum spinosum
  • Large eosinophilic intracytoplasmic inclusion
  • Epidermis is markedly thickened.
  • The superficial layers of the epithelium become necrotic and slough.
  • Vesicle formation is not a feature of this disease.