Difference between revisions of "Insulin Secreting Neoplasms"

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[[Category:Pancreas_-_Hyperplastic_and_Neoplastic_Pathology]][[Category:Endocrine_System_-_Pathology]]
 
[[Category:Pancreas_-_Hyperplastic_and_Neoplastic_Pathology]][[Category:Endocrine_System_-_Pathology]]
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[[Category:To_Do_-_Clinical]][[Category:Neoplasia]]

Revision as of 22:44, 28 June 2010

Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)
  • Adenomas and carcinomas deerived from beta cells
  • Respond rapidly to iv glucose
  • Can be identified by immunocytochemical means
  • Dogs 5-12 years of age most commonly affected
  • Older cattle, associated with periodic convulsions

Clinical signs

  • Hyperinsulinism
  • Hypoglycaemia - often episodic
    • Neurologic signs - stupor, confusion, coma, seizures, peripheral neuropathy may also develop