Difference between revisions of "Equine Adenovirus"

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*Rarely causes primary disease
 
*Rarely causes primary disease
*Exception: immune-compromised Arab foals (showing both B/T cell deficiencies), causing necrotising [[Respiratory Viral Infections - Pathology#Equine adenovirus|bronchiolitis]]
+
*Exception: immune-compromised Arab foals (showing both B/T cell deficiencies), causing necrotising bronchiolitis
  
 
[[Image:Adenovirus in equine lung.jpg|right|thumb|100px|<small><center>Adenovirus in equine lung (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
[[Image:Adenovirus in equine lung.jpg|right|thumb|100px|<small><center>Adenovirus in equine lung (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

Revision as of 13:11, 20 July 2010

  • Rarely causes primary disease
  • Exception: immune-compromised Arab foals (showing both B/T cell deficiencies), causing necrotising bronchiolitis
Adenovirus in equine lung (Image sourced from Bristol Biomed Image Archive with permission)
  • Adenoviridae
  • May cause necrotising bronchiolitis in immune-deficient foals (Arabian foals)
  • Grossly:
    • Atelectasis and consolidation of lobules in cranioventral region
    • Mucopurulent exudate in airways
  • Histologically:
    • Severe bronchiolitis, necrotising -> proliferative
    • Bronchiolar obstruction by sloughed debri and neutrophils -> alveolar atelectasis
  • May lead to secondary bacterial infections