Difference between revisions of "Hepatic Encephalopathy - Horse"

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==Diagnosis==
 
==Diagnosis==
 
===Clinical Signs===
 
===Clinical Signs===
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Clinical signs vary depending on the severity of hepatic dysfunction, early signs are often subtle and may be missed. Clinical signs may be associated with feeding.
 +
 
*Depression
 
*Depression
 
*Lethargy
 
*Lethargy
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==Prognosis==
 
==Prognosis==
Prognosis depends on the underlying disease, signs are potentially reversible if the initiating course can be corrected. However as for most hepatic conditions, the damage is advanced by the time clinical signs are ovident, so most hepatic diseases carry a farily poor prognosis.  
+
Prognosis depends on the underlying disease, signs are potentially reversible if the initiating course can be corrected.  
 +
Horses with hepatic disease showing neurological signs have a poorer prognosis than those showing only signs af hepatic dysfunction. However with appropriate supportive therapy horses can survive for a further 6 months.  
  
 
==References==
 
==References==

Revision as of 11:07, 17 August 2010



See also Hepatic Encephalopathy Pathology

  • the horse may show very little visible neural changes, perhaps an increase in astrocytes

Description

Hepatic encephalopathy is neurological disfunction caused by hepatic disease.

Signalment

Diagnosis

Clinical Signs

Clinical signs vary depending on the severity of hepatic dysfunction, early signs are often subtle and may be missed. Clinical signs may be associated with feeding.

  • Depression
  • Lethargy
  • Head pressing
  • Ataxia
  • Behavioural changes
  • Seizures
  • Coma
  • Death

Clinical signs associated with hepatic disease

  • Weight loos
  • Diarrhoea
  • Icterus


Laboratory Tests

Biopsy

Endoscopy

Pathology

Treatment

Prognosis

Prognosis depends on the underlying disease, signs are potentially reversible if the initiating course can be corrected. Horses with hepatic disease showing neurological signs have a poorer prognosis than those showing only signs af hepatic dysfunction. However with appropriate supportive therapy horses can survive for a further 6 months.

References

  • Knottenbelt, D.C. A Handbook of Equine Medicine for Final Year Students University of Liverpool
  • Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial
  • Rose, R. J. and Hodgson, D. R. (2000) Manual of Equine Practice (Second Edition) Sauders.